Protein Alignment Cyp6a14 and cyp-25A3

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 154/529 - (29%)
• Similarity: 254/529 - (48%)
• Gaps: 67/529 - (12%)

  Fly     1 MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLP--IVGNMRGIVKK---------YHFRD 54
            ::.|..||.:|..:.|.:..:...:..|..:....|.|  ::||::.|:::         |   |
 Worm     4 LILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSY---D 65

  Fly    55 INQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNP---RDDPLTGH 116
            ...:::|:|   |...|:|...:....||:.:.||:|.||:||.|.||   |.|   .|:.|...
 Worm    66 WYNKLHKQF---GETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDR---TPPPIIEDNKLKES 124

  Fly   117 LFALEGEE-WRAMRHKLTPVFTSGKIKQMSKVI---VDVGLRLGDAMDKAVKEAKVEEGNVEIKD 177
            |.....|. |:..|..:.|:|::||:|.|.:.|   ||:.|.:       :||........:|.|
 Worm   125 LLQNTYESGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEI-------LKEKASSGQKWDIYD 182

  Fly   178 LCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTR--RRHSTLVQ-SFIFTNARLARKLRI 239
            .....|.||||.|||.::.|..:|.:..|....|:..|.  .|||.::. ||:|  ..|::..::
 Worm   183 DFQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFITNIDIRHSKIISTSFLF--PELSKLWKV 245

  Fly   240 KVLPDDLTQFFMSTVKNTVD-YRLKNGIKRNDFIEQM-IELRAEDQEAAKKGQGIDLSHGLTLEQ 302
            .....||.:..:..|:...| |..:.|.:.:|.::.: :.|..||          |.|..:|.::
 Worm   246 LYRFTDLAKAEIPLVEGLADVYERRRGGEGSDSVDLLKLLLNRED----------DKSKPMTKQE 300

  Fly   303 MAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLD 367
            :....|.|.:||:||:|:.|:.|.|.|:..|::||:|.|||.....|   |.|.||.:..|.|||
 Worm   301 VIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKEN---GGLTYDSIHNMKYLD 362

  Fly   368 QVLSETLRKHPLLPHLI-RETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRF 431
            .|..||||.:|.:.|.. |...||..|...  ...||.:.:...|.:|.:||.:..||:|.|.||
 Worm   363 YVYKETLRCYPPVIHFSNRRCLKDITIRGQ--FYPKGAIVVCLPHTVHRNPENWDSPEEFHPERF 425

  Fly   432 DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLL 496
            :..|.|: ..:.::|||.|||.|:|:||.:::.|..:..||..|:...         |..::.|:
 Worm   426 ENWEEKS-SSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELKQ---------FEGEADLI 480

  Fly   497 TTNDGIYLK 505
            ...:|:.::
 Worm   481 PDCNGVIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	148/498 (30%)
cyp-25A3	NP_001040850.1	p450	37..496	CDD:278495	148/496 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980