Protein Alignment Cyp6a14 and Cyp6a23

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 246/515 - (47%)
• Similarity: 341/515 - (66%)
• Gaps: 23/515 - (4%)

  Fly     1 MLFTI--ALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKF 63
            :|.|:  .||.::|.:|...|    .||:|:|:||:.|.||.|||:...||.|...|.:..|.|:
  Fly     3 LLLTLIALLVSLLLFMARRRH----GYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKY 63

  Fly    64 K-GQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRA 127
            | ...|.||.|.||.|:|:||||:.:|:|:||||::|::||.|.|..||||:..||::||::||.
  Fly    64 KRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRH 128

  Fly   128 MRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN---VEIKDLCARFTTDVIGS 189
            :||||||.|||||:|.|..:||    ::|:.|:| :..||...|.   :||.||.||:|.||||:
  Fly   129 LRHKLTPTFTSGKMKNMFPIIV----KVGEEMEK-IFSAKTTTGEGQVLEIVDLVARYTADVIGN 188

  Fly   190 CAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTV 254
            |||||.|||||:|:|||...|:.....||:..|:...||...:|:|:||:|:...|:..|:.|.|
  Fly   189 CAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIV 253

  Fly   255 KNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSS 319
            :||:||||:...||:||::.:||:..::|..       :...||:..::.||||:||||||||||
  Fly   254 RNTIDYRLRTNEKRHDFMDSLIEMYEKEQAG-------NTEDGLSFNEILAQAFIFFVAGFETSS 311

  Fly   320 STMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLI 384
            :||...||||||..|||.:||.||.:||:. ...|..|:.:.:|.||:||:.|||||:|:|.||.
  Fly   312 TTMGFALYELALDQDIQDQLRAEINNVLSK-HNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLT 375

  Fly   385 RETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGD 449
            |.|..|:...:....:.||...:||...||:|||||||||||.|.||..|.:..|....:||||:
  Fly   376 RMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGE 440

  Fly   450 GPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKVERV 509
            |||||||||||.:||.:||..|:|.:|||||..|.:|:.|..||.||:..:||:||||::
  Fly   441 GPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	232/477 (49%)
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	229/471 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
	10	10.000