Protein Alignment Cyp6a14 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 130/478 - (27%)
• Similarity: 217/478 - (45%)
• Gaps: 64/478 - (13%)

  Fly    51 HFRDINQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTG 115
            :||||:      ....||:..:........:...|.....|..|:.:.:    .|..|.   |..
  Rat    84 NFRDIH------LSWVGPVYPILRLVHPNVIAPLLQASAAVAPKEMTLY----GFLKPW---LGD 135

  Fly   116 HLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVK--EAKVE------EGN 172
            .|....||:|...|..|||.|....:|...|:           .:|:|.  .||.:      ...
  Rat   136 GLLMSAGEKWNHHRRLLTPAFHFDILKSYVKI-----------FNKSVNTMHAKWQRLTAKGSAR 189

  Fly   173 VEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEF----RQKGREIFTRRRHSTLVQSFIFTNARL 233
            :::.:..:..|.|.:..|.|..:.| .|:.::|:    .:....|..|:|...|...|::.....
  Rat   190 LDMFEHISLMTLDSLQKCIFSFDSN-CQESNSEYIAAILELSSLIVKRQRQPFLYLDFLYYLTAD 253

  Fly   234 ARKLR-----IKVLPDDLTQFFMSTVKNT--VDYRLKNGIKRN--DFIEQMIELRAEDQEAAKKG 289
            .|:.|     :....|.:.:...||: ||  ||..||...|..  |||:  :.|.|:|:.
  Rat   254 GRRFRKACDVVHNFTDAVIRERRSTL-NTQGVDEFLKARAKTKTLDFID--VLLLAKDEH----- 310

  Fly   290 QGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGE 354
                 ..||:...:.|:|..|...|.:|::|.:|..||.||..|:.|:|.|:|:..:|.:.:..|
  Rat   311 -----GKGLSDVDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEE 370

  Fly   355 LNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEI 419
            :.:|.|||:.:|...:.|:||.||.:..:.|..::|..:|:.. |:.||.:.:|.:..:||:|.:
  Rat   371 IEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIVLPDGR-VIPKGNICVISIFGVHHNPSV 434

  Fly   420 YPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTD 484
            :|:||.::|.|||||..:.|.|:|::||..|||||||..|...:.|:.|...|.||.....::..
  Rat   435 WPDPEVYNPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCVLPDDKEP 499

  Fly   485 VPLIFSKKSFLLTTNDGIYLKVE 507
                ..|...:|....|::|:||
  Rat   500 ----RRKPELILRAEGGLWLRVE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	123/458 (27%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	127/474 (27%)