Protein Alignment Cyp6a14 and Cyp3a2

DIOPT Version :10

• Sequence 1: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_063127162.1
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 176/530 - (33%)
• Similarity: 275/530 - (51%)
• Gaps: 68/530 - (12%)

  Fly     2 LFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNM----RGI-------VKKYHFRDI 55
            |.|..|:.|:|.|.|.|.......:|::|:|...|||.:|.:    :|:       .|||
  Rat     9 LETWVLLAVILVLLYRLGTHRHGIFKKQGIPGPKPLPFLGTVLNYYKGLGRFDMECYKKY----- 68

  Fly    56 NQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKD-FSYFQDRGAFTNPRDDPLTG---- 115
             .:|:..|.||.|:..          |.|.:.||.|::|: ||      .|||.||....|
  Rat    69 -GKIWGLFDGQTPVFA----------IMDTEMIKNVLVKECFS------VFTNRRDFGPVGIMGK 116

  Fly   116 HLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLC 179
            .:...:.|||:..|..|:|.||||::|:|..:|.    :.||.:.|.:|: :.|.|. |.:|.:.
  Rat   117 AVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIE----QYGDILVKYLKQ-EAETGKPVTMKKVF 176

  Fly   180 ARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREI-----FTRRRHSTLVQSFIFTNARLARKLRI 239
            ..::.|||.|.:||:..:||.:|...|.:|.:::     |.....|.::..|:   ..:...|.|
  Rat   177 GAYSMDVITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFL---TPIYEMLNI 238

  Fly   240 KVLPDDLTQFFMSTVKNTVDYRL--KNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSH-GLTLE 301
            .:.|.|...||...|....:.||  |:.:.|.||::.|:......::        ::|| .|:..
  Rat   239 CMFPKDSIAFFQKFVHRIKETRLDSKHKVHRVDFLQLMLNAHNNSKD--------EVSHKALSDV 295

  Fly   302 QMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYL 366
            ::.||:.:|..||:||:|||:|..||.||..||||::|:|||:..|.:  .....||::.:|.||
  Rat   296 EIIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPS--KAPPTYDIVMEMEYL 358

  Fly   367 DQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRF 431
            |.||:||||.:|:...|.|...||.::  ..:.:.||.:..||.:.:||||:.:|:||:|.|.||
  Rat   359 DMVLNETLRLYPIGNRLERVCKKDIEL--DGLFIPKGSVVTIPTYALHHDPQHWPKPEEFHPERF 421

  Fly   432 DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLL 496
            ..|...:..|..|||||:|||||||:||..:..|:.|..:|:.|.|.....|.:||..|::: :|
  Rat   422 SKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQA-IL 485

  Fly   497 TTNDGIYLKV 506
            .....|.|||
  Rat   486 EPEKPIVLKV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	151/451 (33%)
Cyp3a2	XP_063127162.1	None