Protein Alignment Cyp6a14 and erg5

DIOPT Version :10

• Sequence 1: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_593788.2
• Gene: erg5 / 2542469
• PomBaseID: SPAC19A8.04
• Length: 543
• Species: Schizosaccharomyces pombe
• Alignment Length: 545
• Identity: 122/545 - (22%)
• Similarity: 229/545 - (42%)
• Gaps: 105/545 - (19%)

  Fly     3 FTIALVGVVLGLAYSLHIKIFSYWKRKG-VP-HETPLPIVGNMRGIVKKYHFRDINQRIYKKFKG 65
            :||....:.:.:||..    .||..:|| :| ....:|.:|:         |.|..:..::|:..
pombe    29 WTICFALLAVCIAYDQ----ISYQMQKGHIPGPRFKIPFMGS---------FLDSMKPTFEKYNA 80

  Fly    66 Q---GPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRA 127
            :   ||::.:.:|.|...:.::.|..::: :...||.|........:....|..:| |:|.:...
pombe    81 KWQTGPLSCVSVFHKFVVIASERDLARKI-LNSPSYVQPCVVDAGKKILKHTNWVF-LDGRDHIE 143

  Fly   128 MRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARF---------T 183
            .|..|..:||:..:......            .:||.....:|.....||..|::         .
pombe   144 YRKGLNGLFTTRALASYLPA------------QEAVYNKYFKEFLAHSKDDYAQYMIPFRDINVA 196

  Fly   184 TDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLTQ 248
            |.....|.:.:..::::..:.|:.:             :..:....|..:       |||.....
pombe   197 TSCRTFCGYYISDDAIKHIADEYWK-------------ITAAMELVNFPI-------VLPFTKVW 241

  Fly   249 FFMSTVKNTVDYRLKNGI--KRN------------DFIEQMIELR---AEDQEAAKKGQGIDLSH 296
            :.:.:.|..:.|.:|...  ::|            ::|.:|||.|   :|::|.|:|..  .|..
pombe   242 YGIQSRKVVMRYFMKAAAESRKNMEAGNAPACMMEEWIHEMIETRKYKSENKEGAEKPS--VLIR 304

  Fly   297 GLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLA 361
            ..:.|:::.....|..|..:.:||.|:.....||..||:.|::|||...:........|:.|::.
pombe   305 EFSDEEISLTFLSFLFASQDATSSAMTWLFQLLADHPDVLQKVREEQLRIRKGDIDVPLSLDLME 369

  Fly   362 QMTYLDQVLSETLRKHP---LLPHLIRET---TKDYQIPNSDIVLDKGILALIP-VHNIHHDPEI 419
            :|||...|:.|.||..|   ::|:.:::.   |.||.:|...:|        || ::...||.::
pombe   370 KMTYTRAVVKECLRLRPPVLMVPYRVKKAFPITPDYTVPKDAMV--------IPTLYGALHDSKV 426

  Fly   420 YPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRF--GKIQAKIGLVSLLRRFKFSVSNR 482
            |||||.|:|.|:.|..:..:.|..::.||:||..|:|.|:  ..:.|.||..|::..:|...:..
pombe   427 YPEPETFNPDRWAPNGLAEQSPKNWMVFGNGPHVCLGQRYAVNHLIACIGKASIMLDWKHKRTPD 491

  Fly   483 TDVPLIFSKKSFLLTT--NDGIYLK 505
            :|..:||:      ||  .|..|||
pombe   492 SDTQMIFA------TTFPQDMCYLK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	105/477 (22%)
erg5	NP_593788.2	CYP61_CYP710	85..507	CDD:410703	105/471 (22%)