Protein Alignment Cyp6a14 and cyp-13A8

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 144/541 - (26%)
• Similarity: 251/541 - (46%)
• Gaps: 107/541 - (19%)

  Fly     1 MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKFKG 65
            |:|.:.|:.:|  ..|..|   :::|||:|:|....:||.|. .|.:.:..|.. ...:.|..|.
 Worm     1 MIFELILISIV--TYYFWH---WTFWKRRGLPGPWGVPIFGK-AGAMLEDSFPP-GYTLQKWTKE 58

  Fly    66 QGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTG--------HLFALEG 122
            .|.|.|.....::..:|:|.|.::::::|.:..|..|      :.:|:.|        |:...:|
 Worm    59 YGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGR------KHNPVQGDPDKDKDIHIVGAQG 117

  Fly   123 EEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN---VEIKDLCARFTT 184
            ..|:.:|....|.|::|.||   ||:.    .:.|:..:.:|:.:.|..|   |.:......:|.
 Worm   118 FRWKRLRTITAPAFSNGSIK---KVLT----TMEDSTQELMKKLREESENGKAVNMHLFYQEYTF 175

  Fly   185 DVIGSCAFGLECNSLQDPSAEFRQ------KGREIFTRRRHSTLVQSFIFTN-----ARLARKLR 238
            |||...|.|      |..|..|:.      ||  .|...|.    |.::|:.     ....:.|.
 Worm   176 DVISRVAMG------QPDSQMFKNPLLKDVKG--FFEHNRW----QIWMFSGGFPFAVSFLKWLF 228

  Fly   239 IK----------VLPDDLTQFFMSTVKNTVDYRLKNGIKRN---DFIEQMIELRAEDQEAAKKGQ 290
            ||          |:...:|...||.:... :...|:|::..   |:|:..:..|||.:..   |:
 Worm   229 IKVGKFGAGPFIVVQKSVTDAVMSRIAQR-EADKKHGVEPGEAADYIDMFLNARAEVEHF---GE 289

  Fly   291 GIDLSH--------GLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVL 347
            ..|..|        .||.:::.:|.|||.||||:|::.::|...|.|||.|.||.:|::|::...
 Worm   290 SNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDKEC 354

  Fly   348 ANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLP-----HLIRETTKDYQIPNSDIVLDKGILAL 407
            .|   .|:.:|.|:::.|:|.|:.|:||..|...     ..:|.|....||      ::.|:..:
 Worm   355 PN---DEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQI------VEAGVDVM 410

  Fly   408 IPVHNIHHDPEIY-PEPEKFDPSRFD----PEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIG 467
            |....:|||..:: .:.|:|.|.|:|    |::       |||.||.|||.|:|:||..::.| |
 Worm   411 IDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQQ-------AYLSFGAGPRVCLGMRFALLEQK-G 467

  Fly   468 LVS-LLRRFKFSVSNRTDVPL 487
            |:| :|:::.|..:.:|.:|:
 Worm   468 LLSHILKKYTFETNAKTQLPI 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	134/510 (26%)
cyp-13A8	NP_496115.1	p450	27..503	CDD:278495	134/510 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134304
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.830