Protein Alignment Cyp6a14 and cyp-13A4

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 145/525 - (27%)
• Similarity: 261/525 - (49%)
• Gaps: 66/525 - (12%)

  Fly     1 MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKK--- 62
            |..::.:.|.:.....:.:|.|:|:|.||||......|..    |::.|:|..: |..:.|.
 Worm     1 MSLSLLIAGALFIGFLTYYIWIWSFWIRKGVKGPRGFPFF----GVILKFHDYE-NPGLLKLGEW 60

  Fly    63 FKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNP-RDDP---LTGHLFALEGE 123
            .|..|.|.|:....::|.::::.:|:.:|.:|.|..|.  |..||| :.||   ...||...:|.
 Worm    61 TKKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFY--GRKTNPIQGDPNKNKRAHLVLAQGH 123

  Fly   124 EWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFTTDVIG 188
            .|:.:|...:|.|::..::::...:.:..:.|...:|:|..:.|.    |::.|....||.|:||
 Worm   124 RWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEASAKGKA----VDLLDYYQEFTLDIIG 184

  Fly   189 SCAFGLECNSLQDPSAEFRQ----KGREIFTRRRHSTLVQSFIFTNA-RLARKLRIKVLPDDLTQ 248
            ..|.|      |..|..||.    |.:|||.:......:.:.:|..| .|.|:|.:| .|.....
 Worm   185 RIAMG------QTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIAGTLMRQLFMK-FPKFSPA 242

  Fly   249 F-FMSTVKNTVDYRL-------KNGIKRN----DFIEQMIELRAE----DQEAA---KKGQGIDL 294
            | .|:|::..::.||       |.||:.:    |||:..::.||.    ::|:.   .|.:.:.:
 Worm   243 FGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLGFAKSEVLKV 307

  Fly   295 SHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDV 359
            ...||.:::..|.|||.:||::|::.::|...|.||..|:||::|:||::   ......|:.:|.
 Worm   308 DKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVD---RECPDPEVTFDQ 369

  Fly   360 LAQMTYLDQVLSETLRKHPL--LPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPE 422
            ::::.|::.|:.|.||.:||  |.| .|:..|...:...:|  |:|....:....:|:||:::.:
 Worm   370 ISKLKYMECVVKEALRMYPLASLVH-NRKCMKKTNVLGVEI--DEGTNVQVDTWTLHYDPKVWGD 431

  Fly   423 PEKFDPSRFDPEEVKNRHPM-----AYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNR 482
                |.|.|.||..:....:     .|||||.|||.|||:|...::.|:.|..:|:::.|..|..
 Worm   432 ----DASEFKPERWETGDELFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTSTE 492

  Fly   483 TDVPL 487
            |::||
 Worm   493 TEIPL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	135/494 (27%)
cyp-13A4	NP_496111.1	p450	33..514	CDD:278495	135/493 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134304
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.830