DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a14 and cyp-25A6

DIOPT Version :9

Sequence 1:	NP_001286199.1	Gene:	Cyp6a14 / 35835	FlyBaseID:	FBgn0033302	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001360017.1	Gene:	cyp-25A6 / 187059	WormBaseID:	WBGene00019438	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	65/233 - (27%)
Similarity:	107/233 - (45%)	Gaps:	34/233 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLP--IVGNMRGIVKK---------YHFRD 54
            ::.|..||.:|..:.|.:..:...:..|..:....|.|  ::||::.|:::         |   |
Worm     4 LILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSY---D 65

  Fly    55 INQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNP---RDDPLTGH 116
            ...:::|:|   |...|:|...:....||:.:.||:|.||:||.|.||   |.|   .|:.|...
Worm    66 WYNKLHKQF---GETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDR---TPPPIIEDNKLKES 124

  Fly   117 LFALEGEE-WRAMRHKLTPVFTSGKIKQMSKVI---VDVGLRLGDAMDKAVKEAKVEEGNVEIKD 177
            |.....|. |:..|..:.|:|::||:|.|.:.|   ||:.|.:       :||........:|.|
Worm   125 LLQNTYESGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEI-------LKEKASSGQKWDIYD 182

  Fly   178 LCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFT 215
            .....|.||||.|||.::.|..:|.:..|....|:..|
Worm   183 DFQGLTLDVIGKCAFAIDSNCQRDRNDIFYVNARKFIT 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	59/202 (29%)
cyp-25A6	NP_001360017.1	p450	37..>215	CDD:386267	57/193 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820