Protein Alignment Cyp6a14 and cyp-13A12

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 137/525 - (26%)
• Similarity: 258/525 - (49%)
• Gaps: 77/525 - (14%)

  Fly     5 IALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKFKGQGPI 69
            :|::..::|: .|.::..:|||||:|:...:..||:|:...::...:...:..:.:.  |..|.:
 Worm     6 LAILTSIIGV-LSFYLWTWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKEWT--KQYGKV 67

  Fly    70 AGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTG--------HLFALEGEEWR 126
            .|:.....||.:|:|.|.:::|.:|.:..|..|      :.:|:.|        :||:.:|..|:
 Worm    68 YGITEGLSRTLVISDPDLVQEVFVKQYDNFFGR------KLNPIQGDPNKDKRVNLFSSQGHRWK 126

  Fly   127 AMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLCARFTTDVIGSC 190
            .:|...:|.|::..::::...:.:..:.|...:     |...:.|. :::.|....||.||||..
 Worm   127 RLRTISSPTFSNNSLRKLKTTVEECAVELLRHI-----EQHTDGGQPIDLLDFYQEFTLDVIGRI 186

  Fly   191 AFGLECNSLQDPSAEFRQK----GREIFTRRRHSTLVQSFIFTNARLA------RKLRIKVLPDD 245
            |.|      |..|..|:..    .|.:|...|..      :|.:..||      .::.:..||:.
 Worm   187 AMG------QTDSQMFKNPLLPYVRAVFGEPRKG------LFLSGSLAPWIGPILRMVMFSLPNI 239

  Fly   246 LTQFFMSTVK---NTVDYRL-------KNGI---KRNDFIEQMIELRAEDQEAAKKGQ----GID 293
            :....:..::   |.|:.|:       |.||   :..|||:..::.:::|.|......    |:.
 Worm   240 VKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVK 304

  Fly   294 LSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYD 358
            ::..||.|::..|.|||.:|||:|::.::|...:.||..|.:|::|:|||:...|:   .|:.:|
 Worm   305 VTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDRECAD---PEVTFD 366

  Fly   359 VLAQMTYLDQVLSETLRKHPL--LPH---LIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPE 418
            .|:::.|::.|:.||||.:||  |.:   .:|.|    :|.|.:|  |:|...|.....:|.|..
 Worm   367 QLSKLKYMECVIKETLRMYPLGALANSRCCMRAT----KIGNYEI--DEGTNILCDTWTLHSDKS 425

  Fly   419 IYPE-PEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNR 482
            |:.| .|:|.|.|::..:........|:|||.|||.|||:|...::.|:.|..:||::...|.|:
 Worm   426 IWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNK 490

  Fly   483 TDVPL 487
            |.:||
 Worm   491 TQIPL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	128/498 (26%)
cyp-13A12	NP_499705.1	p450	33..507	CDD:278495	128/497 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134304
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.830