Protein Alignment Cyp6a14 and cyp-25A2

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 152/524 - (29%)
• Similarity: 251/524 - (47%)
• Gaps: 57/524 - (10%)

  Fly     1 MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLP--IVGNMRGIV---KKYHFRDINQRIY 60
            ::.|..|:.:|..:.|.|..:...:..|:.:....|.|  .:||::.||   :|..:.|.|:...
 Worm     4 LILTSILILLVSFIIYILFARREQFKLREKIGLTGPEPHWFMGNLKQIVDRKEKLGYDDSNKWFN 68

  Fly    61 KKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDR---GAF-TNPRDDPLTGHLFALE 121
            :..|..|...|:|...:...::::.:.||:|.||:||.|.||   ..| :|..:..|..:.:|
 Worm    69 ELHKQYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNTYA-- 131

  Fly   122 GEEWRAMRHKLTPVFTSGKIKQMSKVI---VDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFT 183
             ..|:..|..:.|:|::||:|.|.:.|   ||:.|.:       ::|........:|.:.....|
 Worm   132 -TGWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDI-------LREKASSGQKWDIYEDFQGLT 188

  Fly   184 TDVIGSCAFGLECNSLQDPSAEFRQKGREIFTR--RRHSTLV-QSFIFTN-ARLARKLRIKVLPD 244
            .||||.|||.::.|..:|.:..|....|:....  .|||.:: .|||... |.|.|.| .|..|
 Worm   189 LDVIGKCAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVIAASFILPELAPLWRAL-YKYTP- 251

  Fly   245 DLTQFFMSTVKNTVD-YRLKNGIKRNDFIEQM-IELRAEDQEAAKKGQGIDLSHGLTLEQMAAQA 307
             |....:..|:...: |..:.|.:.:|.::.: :.|..||          |.|..:|.:::....
 Worm   252 -LADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLNRED----------DKSKPMTKQEVIENC 305

  Fly   308 FVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSE 372
            |.|.:||:||:|:.|:.|.|.|:..|::||:|.|||.....|   |.|.||.:..|.|||.|..|
 Worm   306 FAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKEN---GGLTYDSIHNMKYLDYVYKE 367

  Fly   373 TLRKHPLLPHLI-RETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEV 436
            |||.:|.:.|.| |....|..|...  ...||.:.....|.:|.:||.:..||:|.|.||:..|.
 Worm   368 TLRCYPPVIHFINRRCLADITIRGQ--FYPKGSVVTCLPHTVHLNPENWDSPEEFHPERFENWEE 430

  Fly   437 KNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDG 501
            |: ..:.::|||.|||.|:|:||.:::.|..:|.||..|:...         |..::.|:...:|
 Worm   431 KS-SSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQ---------FKGEADLIPDCNG 485

  Fly   502 IYLK 505
            :.::
 Worm   486 VIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	146/493 (30%)
cyp-25A2	NP_497776.2	p450	38..498	CDD:278495	146/490 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980