Protein Alignment Cyp6a14 and Cyp3a62

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 178/510 - (34%)
• Similarity: 278/510 - (54%)
• Gaps: 53/510 - (10%)

  Fly     2 LFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKFKGQ 66
            |.|..|:..:|.|.|.........:|:.|:....|||.|||:  :..::.|.:.::..:||:
  Rat     9 LETWMLLATILVLLYLYGTSTHGNFKKLGISGPKPLPFVGNI--LAYRHGFWEFDRHCHKKY--- 68

  Fly    67 GPIAGMYMFFKRTALITDLDFIKQVMIKD-FSYFQDRGAFTNPRDDP---LTGHLFALEGEEWRA 127
            |.|.|.|...:....|||.|.||.|::|: :|.|.:|.:|     .|   |...:...|.|||:.
  Rat    69 GDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSF-----GPAGILKKAITLSEDEEWKR 128

  Fly   128 MRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLCARFTTDVIGSCA 191
            :|..|:|.|||||:|:|..:|    .:..|.:.|.||. :.|:|| :.:||:...::.|||...:
  Rat   129 LRTLLSPTFTSGKLKEMFPII----NQYADLLVKNVKH-EAEKGNPITMKDIFGAYSMDVITGTS 188

  Fly   192 FGLECNSLQDPSAEFRQKGREI---------FTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLT 247
            ||:..:||.:|...|.||.:::         |.    |.::..|:   ..:.....|.|.|.|:.
  Rat   189 FGVNVDSLNNPQNPFVQKVKKLLKFNFLDPFFL----SVILFPFL---TPVFEAFDITVFPKDVM 246

  Fly   248 QFFMSTVKNTVDYRLKNGIK-RNDFIEQMIELRAE-DQEAAKKGQGIDLSH-GLTLEQMAAQAFV 309
            :||.::|:...:.|::..:| |.||::.||..::. |:|          || |||..::.||:..
  Rat   247 KFFRTSVERMKENRMQEKVKQRLDFLQLMINSQSSGDKE----------SHQGLTDVEIVAQSIF 301

  Fly   310 FFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETL 374
            |..||:||:||.:|..||.||..||:|::|::||::.|.|  ...:.||||.:|.|||.||:|||
  Rat   302 FIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAALPN--KAPVTYDVLVEMEYLDMVLNETL 364

  Fly   375 RKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNR 439
            |..|:...|.|...||.:|  :.:.:.||.:.::|...:|.||:.:||||:|.|.||..:...:.
  Rat   365 RLFPVGGRLERVCKKDVEI--NGVFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSI 427

  Fly   440 HPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSF 494
            :|..|||||:|||||||:||..:..||.||.:|:.|.|.:...|.:||...||.|
  Rat   428 NPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGLCKETQIPLKLRKKGF 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	170/480 (35%)
Cyp3a62	NP_001019403.1	p450	39..491	CDD:278495	170/480 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134304
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.870