Protein Alignment Cyp6a14 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 449
• Identity: 123/449 - (27%)
• Similarity: 216/449 - (48%)
• Gaps: 57/449 - (12%)

  Fly    81 LITDLDFIKQVMIKD-------FSYFQDRGAFTNPRDDPLTGH-LFALEGEEWRAMRHKLTPVFT 137
            |:.|.|::|.|:.:.       :.:|.           |..|: |..|.|::|...|..|||.|.
Mouse    95 LLYDPDYVKVVLGRSDPKASGIYQFFA-----------PWIGYGLLLLNGKKWFQHRRMLTPAFH 148

  Fly   138 SGKIKQMSKVIVD-VGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFTTDVIGSCAFGLECNSLQD 201
            ...:|...|::.| |.:.|    ||..| ...::..:||....:..|.|.:..|||..:.:...|
Mouse   149 YDILKPYVKIMADSVNIML----DKWEK-LDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLD 208

  Fly   202 PSAEFRQKGRE-----IFTRRRHSTLVQSFIF---TNARLARKLRIKVL---PDDLTQFFMSTVK 255
            .:::...|..|     .|.|.|::....:.|:   ::.||:.. ..::.   .|.:.:...|.::
Mouse   209 ENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHH-ACQIAHEHTDGVIKMRKSQLQ 272

  Fly   256 NTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSS 320
            |..:.:.....:..||::.::..|.||:            :.|:.|.:.|:...|...|.:|::|
Mouse   273 NEEELQKARKKRHLDFLDILLFARMEDR------------NSLSDEDLRAEVDTFMFEGHDTTAS 325

  Fly   321 TMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIR 385
            .:|...|.||..|:.|||.|||::|:|.  ||..:.:|.|.||.|....:.|.||.:|.:..:.|
Mouse   326 GISWIFYALATHPEHQQRCREEVQSILG--DGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSR 388

  Fly   386 ETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDG 450
            |.:.....|:...: .|||.|.|.::.:||:|..:|.|:.||||||.|:  .:.|..|||||..|
Mouse   389 ELSSPVTFPDGRSI-PKGITATISIYGLHHNPRFWPNPKVFDPSRFAPD--SSHHSHAYLPFSGG 450

  Fly   451 PRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKVERV 509
            .|||||.:|...:.|:.:...|.||:. :.:.|.:|:..::  .:|.:.:||:|.::::
Mouse   451 SRNCIGKQFAMNELKVAVALTLLRFEL-LPDPTRIPVPIAR--LVLKSKNGIHLCLKKL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	121/441 (27%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	122/443 (28%)