Protein Alignment Cyp6a14 and Cyp3a16

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 520
• Identity: 179/520 - (34%)
• Similarity: 270/520 - (51%)
• Gaps: 49/520 - (9%)

  Fly     2 LFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNM----RGIVKKYHFRDINQRIYKK 62
            |.|:.|:.::|.|.|.........:|::|:|...|||.:|.:    :|:.|      .:...|:|
Mouse     9 LDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWK------FDMECYEK 67

  Fly    63 F-KGQGPIAGMYMFFKRTALITDLDFIKQVMIKD-FSYFQDRGAFTNPRD----DPLTGHLFALE 121
            : |..|...|....|    :|||.:.||.|::|: ||      .|||.:|    ..::..:...:
Mouse    68 YGKTWGLFDGQIPLF----VITDPETIKNVLVKECFS------VFTNRQDFFPVGIMSKSISLAK 122

  Fly   122 GEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLCARFTTD 185
            .|||:..|..|:|.||||.:|:|..||.    :.||.:.|.::: :.|:|. |.:||:...::.|
Mouse   123 DEEWKRYRALLSPTFTSGNLKEMFPVIE----QYGDILVKYLRQ-EAEKGKPVAVKDVLGAYSMD 182

  Fly   186 VIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTL---VQSFIFTNARLARKLRIKVLPDDLT 247
            ||.|..||:..:||.:|...|.:..:::........|   |..|.|... :...|.|.:.|.|..
Mouse   183 VIISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTP-IYEMLNICMFPKDSI 246

  Fly   248 QFFMSTVKNTVDYRLKNGIK-RNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFF 311
            :||...|....:.||.:..| |.|||..|:       ||..|.:..|....|:..::.||:.:|.
Mouse   247 EFFKKFVDRMTENRLDSKQKHRVDFIYLMM-------EAYNKSKDKDSHKALSEIEITAQSIIFI 304

  Fly   312 VAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRK 376
            .||:||:||.:|..:|.||..||||::|:|||:..|.|  .....||.:..|.|||.||:||||.
Mouse   305 FAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPN--KAPPTYDTVMAMEYLDMVLNETLRL 367

  Fly   377 HPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHP 441
            :|:...|.|...||.:|  :.|.:.||...:||.:.:||||:.:||||:|.|.||..|...:..|
Mouse   368 YPITNRLQRVCKKDVEI--NGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDP 430

  Fly   442 MAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKV 506
            ..|||||:|||||||:||..:..|:.|:.:|:.|.|.....|.:||..|:: .||.....|.|||
Mouse   431 YVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSRE-LLLQPVKPIVLKV 494

  Fly   507  506
            Mouse   495  494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	169/488 (35%)
Cyp3a16	NP_031846.2	p450	39..494	CDD:278495	169/488 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820