Protein Alignment Cyp6a14 and Cyp26a1

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 507
• Identity: 109/507 - (21%)
• Similarity: 195/507 - (38%)
• Gaps: 140/507 - (27%)

  Fly    32 PHETPLPIVG-NMRGIVKKYHFRDINQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKD 95
            |.....|..| .::.::::..|..:.:|.|      |.|...::|.:.|..:...|.::::::
Mouse    46 PGTMGFPFFGETLQMVLQRRKFLQMKRRKY------GFIYKTHLFGRPTVRVMGADNVRRILL-- 102

  Fly    96 FSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGL--RLGDA 158
                                      ||      |:|..|.....:    :.|:..|.  .|.|:
Mouse   103 --------------------------GE------HRLVSVHWPASV----RTILGAGCLSNLHDS 131

  Fly   159 MDKAVKEAKVEEGNVEIKDLCARFTTDVIGSC-AFGLECNSLQDPSAEFRQKGREIFTRRRHSTL 222
            ..|..|:..::..:.|..........:.:.|| ...|.|.          ::|..::..
Mouse   132 SHKQRKKVIMQAFSREALQCYVPVIAEEVSSCLEQWLSCG----------ERGLLVYPE------ 180

  Fly   223 VQSFIFTNARLARKLRIKVLP---------DDLTQFFMSTVKN----TVD------YRLKNGIKR 268
            |:..:|   |:|.::.:...|         ..|.:.|....:|    .:|      ||   |:|.
Mouse   181 VKRLMF---RIAMRILLGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPIDVPFSGLYR---GVKA 239

  Fly   269 NDFIEQMIE---------LRAEDQEAA-------------KKGQGIDLSHGLTLEQMAAQAFVFF 311
            .:.|...||         |:|.:.:..             ::|:.:|:.   .|:|.:.:   ..
Mouse   240 RNLIHARIEENIRAKIRRLQATEPDGGCKDALQLLIEHSWERGERLDMQ---ALKQSSTE---LL 298

  Fly   312 VAGFETSSSTMSLCLYELALQPDIQQRLREEIES----VLANVDGGELNYDVLAQMTYLDQVLSE 372
            ..|.||::|..:..:..|.|.|.:.|::||||:|    ..:|.| .:|:.:.|.|:.|...|:.|
Mouse   299 FGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQD-NKLDMETLEQLKYTGCVIKE 362

  Fly   373 TLRKHPLLPHLIRETTK-----DYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRF- 431
            |||.:|.:|...|...|     .||||       ||...:..:.:.|...:|:...|:|:|.||
Mouse   363 TLRLNPPVPGGFRVALKTFELNGYQIP-------KGWNVIYSICDTHDVADIFTNKEEFNPDRFI 420

  Fly   432 --DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSN 481
              .||:...   .:::|||.|.|:|:|..|.||..||..|.|.|...:.:.|
Mouse   421 VPHPEDASR---FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	109/507 (21%)
Cyp26a1	NP_031837.2	p450	43..491	CDD:299894	109/507 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940