Protein Alignment Cyp6a14 and Cyp4f15

DIOPT Version :10

• Sequence 1: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 481
• Identity: 129/481 - (26%)
• Similarity: 217/481 - (45%)
• Gaps: 89/481 - (18%)

  Fly    67 GPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHK 131
            |||..:........:.:.|:....|.:|:..::    :|..|.   |...|...:|::|.:.|..
Mouse    98 GPIIPIITLCHPDIIRSVLNASASVALKEVVFY----SFLKPW---LGDGLLLSDGDKWSSHRRM 155

  Fly   132 LTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVE------EGNVEIKDLCARFTTDVIGSC 190
            |||.|....:|...|:..|         ...:..||.:      ...:::.:..:..|.|.:..|
Mouse   156 LTPAFHFNILKPYVKIFND---------STNIMHAKWQHLASGGSARLDVFENISLMTLDSLQKC 211

  Fly   191 AFGLECNSLQDPSAEFRQKGRE---IFTRRRHSTL--VQSFI------------------FTNAR 232
            .|..:.|..::|| |:.....|   :.|:|.|..|  :.|..                  ||:|.
Mouse   212 VFSFDSNCQENPS-EYISAILELSALVTKRYHQLLLHIDSLYQLTCSGRRFHKACHLVHSFTDAV 275

  Fly   233 LARKLRIKVLP----DDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGID 293
            :..:.|  .||    ||:             .:.|...|..|||:.::..:.||        |.:
Mouse   276 IQDRRR--TLPSKHEDDV-------------LKAKAKSKTLDFIDVLLLSKDED--------GKE 317

  Fly   294 LSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELN-- 356
            ||.    |.:.|:|..|...|.:|::|.:|..||.||..|:.|:|.|:|::.:|.:.:..|:.
Mouse   318 LSD----EDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRDRESTEIECS 378

  Fly   357 -----YDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHD 416
                 .|.|||:.:|...:.|:||.||.:..:.|..|:|..:|:.. |:.||::.:|.:...||:
Mouse   379 CAVFLRDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGR-VIPKGVICIINIFATHHN 442

  Fly   417 PEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSN 481
            |.::|:||.:||.|||||.:|:|.|:|::||..|||||||..|...:.|:.|...|.||:....:
Mouse   443 PTVWPDPEVYDPFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLPDD 507

  Fly   482 RTDVPLIFSKKSFLLTTNDGIYLKVE 507
            :..    ..|...:|....|::|:||
Mouse   508 KEP----RRKPELILRAEGGLWLRVE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	126/475 (27%)
Cyp4f15	NP_598888.1	CYP4F	79..527	CDD:410772	126/477 (26%)