Protein Alignment mtt and olfcn1

DIOPT Version :10

• Sequence 1: NP_001260806.1
• Gene: mtt / 35832
• FlyBaseID: FBgn0050361
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: XP_073785910.1
• Gene: olfcn1 / 793310
• ZFINID: ZDB-GENE-061117-2
• Length: 1188
• Species: Danio rerio
• Alignment Length: 812
• Identity: 236/812 - (29%)
• Similarity: 396/812 - (48%)
• Gaps: 80/812 - (9%)

  Fly   424 LEAMLFTIDRINR-EQLLPNITLGAHILDDCDKDSYGLEMAVDFIKGSISNIDDAEYHCNKTQVR 487
            :::|:|.:|.||: |:|||:|:||..|:|.|...:..|......    :|...:.|:   .:|..
Zfish   410 IQSMMFAVDEINKNEELLPHISLGYKIMDSCASPTNVLRAVFSL----VSEQKEQEF---TSQCH 467

  Fly   488 KVISGVVGAASSVTSIQVANLLRLFRIPQVSYFSTSPELSNKQRFEYFSRTIPSDHYQVKAMVEI 552
            ..::.:|..:.|..|:.||.:|..||:|.||||||...||:::::..|.||||||.||.||:..:
Zfish   468 LPLTALVAESGSSQSLAVAGMLGPFRVPMVSYFSTCACLSDRKKYPSFFRTIPSDFYQAKALASL 532

  Fly   553 VKRMGWSYVSIIYEESNY---GIKAF-EELEELLARHNICIAIKEKLVK---DSGVAEDIAYDNI 610
            ||:.||:::..:..:::|   ||.|| :|:|::    .:|||....:::   .|.:.|
Zfish   533 VKQFGWTWIGALQSDNDYGRNGISAFTKEVEKM----GVCIAFVGTILRTYPQSKITE------- 586

  Fly   611 VQKLLTKPRARGAIIFGSDQEVRQVMRAVRRANATGSFSWIGSDGW--SARNLVSDDYEPEVEGT 673
            |.:::.:...:..:.|..:.::..:|:.|...|.|| ..||.|:.|  :||....:.:: ...||
Zfish   587 VVEMIKESTVKVILAFVPEGDLYPLMKEVVNRNITG-IQWIASEAWVTAARPSTPEMFK-SFGGT 649

  Fly   674 LSVQPQANPVRGFEEYFLSLTVENNQRNPWFVEFWEDHFQCRYPGSTSTPYNNYT---KQCTTKE 735
            :....:...:.....|..:::..:..::.:..:|||....|: |.....|..|.|   :.||.:|
Zfish   650 VGFVVRKMAMLKLRPYLENISPYSPTQSAFVSDFWETVVGCK-PCLNCEPSANSTLNGQMCTGQE 713

  Fly   736 RLSRQNTD-FEDQLQF-----VSDAVMAFAYALRDMHRDL-CGGGPSLCE------AMKPTKGAD 787
            :|:  .|| |.|..|.     |..||.|.|:|:   |:.| |.|..:|.:      .:.|.:.:|
Zfish   714 KLT--FTDKFFDVTQVRVTYNVYQAVYAIAHAI---HKVLYCQGDNNLSKMCLNVSQITPKQVSD 773

  Fly   788 LLKYLRKVEFEGLSGDEFRFDGNGDGPARYNIIHFKQSQAGQYHWVKVGEYT---EGELRLNMTE 849
               .|.:|.|....|:...||.|||.||.|.:|:::.:| |:...|.||.::   :|..:|.:.|
Zfish   774 ---QLERVNFIDEYGENVFFDENGDPPASYELINWQLNQ-GEVQHVTVGYFSKSPDGTYKLTIKE 834

  Fly   850 VKF----KRLSPKPPESVCSLPCLVGQAKKYVEGES-CCWHCFNCTTYQIRHPDDETHCKLCKLG 909
            ...    :.|.||   :|||..|..|..|..::|.. ||:.|..|....|.:......|.||...
Zfish   835 DNVHWSTENLIPK---AVCSDTCPKGTRKAQIKGRPVCCFDCIPCADGSISNTTGAADCTLCPKE 896

  Fly   910 TLPDAHKQYCRPIPEIYLRPESAWAIGAMAFSATGILVTLFVMGVFVRHNDTPIVRASGRELSYI 974
            ...:..:..|......:|.......|...|.|..|..:|:..|.||:.:.:||||:|:..|||.:
Zfish   897 YWSNERRDKCLVKTIEFLSYTETMGIILTALSLFGASLTVATMIVFIHYRETPIVKANNSELSSL 961

  Fly   975 LLAGIFMCYGVTFALVLKPTNIVCAIQRFGVGFCFTVVYAALLTKTNRIARIFKAGKQSAKRPSF 1039
            ||:.:|.|:......:.:||:..|.::....|..|.:..:.:|.||..:...|:|.....|....
Zfish   962 LLSSLFFCFLCPLTFIGEPTHWSCMLRHTAFGLTFALCISCVLGKTIVVVTAFRATLPGNKLSGK 1026

  Fly  1040 ISPKSQLVICACLVSVQILINGVWMVIAPSHAMHHYP---TREDN---LLVCDSYIDASYMIAFS 1098
            ..|..|..|.....::||:|..:|::|.|.     :|   .|.|:   :|.|::..||.:..|..
Zfish  1027 FGPVQQRAIVFLCTAIQIVICALWLLIKPP-----FPDKALRYDHKKIILECNTGSDAGFYAALG 1086

  Fly  1099 YPIFLIVICTVYAVLTRKIPEAFNESKHIGFTMYTTCVIWLAFVPLYFGTANHVPLRITSMSVTI 1163
            |...|..||.:.|.|.||:|:.|||:|.|.|:|...|.:|:.|:|.|..:.....:.:...:  |
Zfish  1087 YVGLLSTICLILAFLGRKLPDNFNEAKFISFSMLIFCAVWVTFIPAYISSPGKYTVAVEIFA--I 1149

  Fly  1164 SLSASVTIACLFSPKLYIILIRPERNVRQSMM 1195
            ..||...:.|:|:||.:||||:||||.|:.:|
Zfish  1150 LSSAFGLLLCIFAPKCFIILIKPERNTRKHVM 1181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtt	NP_001260806.1	Periplasmic_Binding_Protein_type1	73..>157	CDD:471960
		PBP1_mGluR	393..848	CDD:380585	129/452 (29%)
		NCD3G	860..912	CDD:462210	15/52 (29%)
		7tmC_mGluRs	932..1184	CDD:320173	78/257 (30%)
		TM helix 1	932..957	CDD:320173	8/24 (33%)
		TM helix 2	969..990	CDD:320173	7/20 (35%)
		TM helix 3	999..1023	CDD:320173	5/23 (22%)
		TM helix 4	1045..1065	CDD:320173	6/19 (32%)
		TM helix 5	1089..1115	CDD:320173	9/25 (36%)
		TM helix 6	1123..1146	CDD:320173	9/22 (41%)
		TM helix 7	1153..1178	CDD:320173	5/24 (21%)
olfcn1	XP_073785910.1	None