Protein Alignment Mal-A8 and MAL12

DIOPT Version :10

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_011808.3
• Gene: MAL12 / 853209
• SGDID: S000003524
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 621
• Identity: 192/621 - (30%)
• Similarity: 282/621 - (45%)
• Gaps: 104/621 - (16%)

  Fly    24 SSSSETTKDWWQTAQFYQIYPRSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPMVD 88
            |...||...||:.|..|||||.|||||:.||.|||.||||||:|:|||||.|.|:.|.:.||..|
Yeast     4 SDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQD 68

  Fly    89 FGYDISDFFDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKS-VKREKGYEDY 152
            .|||||::..:.|.|||.||...||.:..:|.:|.:.|.|.||.|.|.|||.:| ..:.....|:
Yeast    69 MGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDW 133

  Fly   153 YVWHDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKRV 217
            :.|...|.....||..||.||..:|.||||.::|...::||..||.:|.|||:.|    |..:|.
Yeast   134 FFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWEN----EDCRRA 194

  Fly   218 L-----RYWLNEGVSGFRCD---------ALP--PLFEVVPDSDGQFPDEVVSGATEDKEDRDYL 266
            :     .:||:.||.|||.|         .||  |:|:  ..|..|.|:   .|:.......:|.
Yeast   195 IFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFD--KTSKLQHPN---WGSHNGPRIHEYH 254

  Fly   267 TT--TYIENQPETIDMVYQWRTVLDDHKRIFGGNSSVLLIETYSPAWFTMQFYGNRSTEGAHLP- 328
            ..  .:::|:      |...|.::...:...|.:::   :.|.:..:...:.:.....|....|
Yeast   255 QELHRFMKNR------VKDGREIMTVGEVAHGSDNA---LYTSAARYEVSEVFSFTHVEVGTSPF 310

  Fly   329 FNFNLI--TVMEQSGLSASNVQEAIDLWLKNMPAGRTPNWV---LGNHDKRRAASRYGKEN---- 384
            |.:|::  |:.:.....|||.     |::..     |.:|.   :.|||:.|:.:|:..::
Yeast   311 FRYNIVPFTLKQWKEAIASNF-----LFING-----TDSWATTYIENHDQARSITRFADDSPKYR 365

  Fly   385 -IDG--MNMLVMILPGVSVTYQGEEIGM-------------TDGEISWEDTVDPWGCNSN--PNI 431
             |.|  :.:|...|.|....|||:|||.             .|.:.::|.....:|.||.  .:.
Yeast   366 KISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDF 430

  Fly   432 YE---QYTRDPERTPFQWT-GGTNAGFTNGS-STWLPLAADYAT-INVEKELSDDHSHLKIYKAL 490
            ::   ..:||..|||..|| ...|||||... ..|..|...:.. ||||:|..||.|.|..:|..
Yeast   431 FKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRA 495

  Fly   491 VALRKSSKTLQNGSTKYQAL---SEDIFVVQRSLTK---SATIVLVINFGSVAKTVDLSQFDKSR 549
            :..||..|.|......:|.:   |:.||    |.||   ..|:...:||..     :..:|...|
Yeast   496 LQARKKYKELMIYGYDFQFIDLDSDQIF----SFTKEYEDKTLFAALNFSG-----EEIEFSLPR 551

  Fly   550 T-ESLQLLIRSIDSTKKEGTRYDPKALSLDPSEALV 584
            . .||..::.:.|.|       |..:..|.|.|..:
Yeast   552 EGASLSFILGNYDDT-------DVSSRVLKPWEGRI 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	169/528 (32%)
MAL12	NP_011808.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	164/513 (32%)
		Malt_amylase_C	511..583	CDD:435493	20/86 (23%)