Protein Alignment Mal-A8 and IMA1

DIOPT Version :10

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_011803.3
• Gene: IMA1 / 853204
• SGDID: S000003519
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 624
• Identity: 193/624 - (30%)
• Similarity: 289/624 - (46%)
• Gaps: 94/624 - (15%)

  Fly    22 VQSSSSETTKDWWQTAQFYQIYPRSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPM 86
            :.|:..||...||:.|.||||||.|||||:.||.||:.||.|||||:|:||..|.|:||.:.||.
Yeast     3 ISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQ 67

  Fly    87 VDFGYDISDFFDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKS-VKREKGYE 150
            .|.||||:::..:.|.|||.||...||::..:|.:|.:.|.|.||.|:|.|||.:| ..:.....
Yeast    68 DDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKR 132

  Fly   151 DYYVWHDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMK 215
            |::.|...|.....||..||.||..||.||||.::|..|::||..|...|||||:.|    |..:
Yeast   133 DWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWEN----EDCR 193

  Fly   216 RVL-----RYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIENQP 275
            :.:     .|||:.||.|||.|......:||     ..||..|    .||      .:|:..:.|
Yeast   194 KAIYESAVGYWLDHGVDGFRIDVGSLYSKVV-----GLPDAPV----VDK------NSTWQSSDP 243

  Fly   276 ETID--MVYQWRTVLDD--HKRIFGGNSSVLLIETYSPAWFTMQFYGNRSTEGAHLPFNFNLITV 336
            .|::  .::::...::.  ..|:..|...:.:.|....:..|.:.|.:.|.......|||:...|
Yeast   244 YTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSELFNFSHTDV 308

  Fly   337 MEQSGLSASNVQEAIDLWLKNMP---------AGRTPNW---VLGNHDKRRAASRYGKEN----- 384
                |.|.......:...||:..         ...|..|   .|.|||:.|:.:|:|.::
Yeast   309 ----GTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRFGDDSPKNRV 369

  Fly   385 IDG--MNMLVMILPGVSVTYQGEEIGMTDGEISW--EDTVDPWGCNSNPNIYEQY---------- 435
            |.|  :::|:..|.|....|||:|:|..:.: :|  |...|....|:...|.|::
Yeast   370 ISGKLLSVLLSALTGTLYVYQGQELGQINFK-NWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKF 433

  Fly   436 -------TRDPERTPFQWT-GGTNAGFTNGSS-TWLPLAADYAT-INVEKELSDDHSHLKIYKAL 490
                   :||..|||.||: ...||||:..|: .|..|...:.. ||||.|:.|.:|.|..:|..
Yeast   434 LEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEA 498

  Fly   491 VALRKSSKTLQNGSTKYQALSED---IFVVQRSLTK---SATIVLVINFGSVAKTVDLSQFDKSR 549
            :..||:.|.:......::.:..|   :|    |.||   :.|:...:||.|.|....:...|.|
Yeast   499 LKFRKAHKDITVYGYDFEFIDLDNKKLF----SFTKKYNNKTLFAALNFSSDATDFKIPNDDSS- 558

  Fly   550 TESLQLLIRSIDSTKKEGTRYDPKALSLDPSEALVLTTE 588
                 ..:...:..|||   .|..:.:|.|.|..:..:|
Yeast   559 -----FKLEFGNYPKKE---VDASSRTLKPWEGRIYISE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	170/526 (32%)
IMA1	NP_011803.3	AmyAc_SI_OligoGlu_DGase	16..503	CDD:200472	165/510 (32%)
		Malt_amylase_C	514..585	CDD:445893	19/83 (23%)