Protein Alignment Mal-A8 and SLC3A2

DIOPT Version :10

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001012680.1
• Gene: SLC3A2 / 6520
• HGNCID: 11026
• Length: 631
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 118/568 - (20%)
• Similarity: 193/568 - (33%)
• Gaps: 176/568 - (30%)

  Fly    33 WWQTAQFYQIYPRSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPMVDFGYDISDFF 97
            ||.|...|:|  ...:...|.|.|:|.|:..:|:||..|.|....|.||.|:...|...  :|..
Human   219 WWHTGALYRI--GDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQ--TDLL 279

  Fly    98 DIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKSVKREKGYEDYYVWHDGKVNS 162
            .|.|.:|:.|||.:|::.||:..::::||..||: ..|:.||...|
Human   280 QIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNY-RGENSWFSTQV------------------- 324

  Fly   163 TTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKRVLRYWLNEGVS 227
                                                         ..|..::|..|.:||..||.
Human   325 ---------------------------------------------DTVATKVKDALEFWLQAGVD 344

  Fly   228 GFRCDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIENQPETIDMVYQWRTVL---- 288
            ||:.                               ||      |||..:....:.:|:.:.
Human   345 GFQV-------------------------------RD------IENLKDASSFLAEWQNITKGFS 372

  Fly   289 DDHKRIFGGNSSVL-----LIETYSPAWFTMQFYGNRSTEGAHLPFNFNLITVMEQSGLSASNVQ 348
            :|...|.|.|||.|     |:|:......|..:..:..:.|.|..   :|:|
Human   373 EDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTK---SLVT------------- 421

  Fly   349 EAIDLWLKNMPAGRTPNWVLGNHDKRRAASRYGKENIDGMNMLVMILPGVSVTYQGEEIGMTDGE 413
                 ...|....|..:|.|.  ..|...|....:.:....:::..|||..|...|:|||:....
Human   422 -----QYLNATGNRWCSWSLS--QARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAA 479

  Fly   414 ISWEDTVDP---WGCNSNPNIYEQYTRDPERTPFQWTGGTNAGFTNGSSTWLPLAADYATINVEK 475
            :..:....|   |..:|.|:|               .|..:|..|                 |:.
Human   480 LPGQPMEAPVMLWDESSFPDI---------------PGAVSANMT-----------------VKG 512

  Fly   476 ELSDDHSHLKIYKALVALRKSSKTLQNGSTKYQALSEDIFVVQRSLTKSATIVLVINFGSVAKTV 540
            :..|..|.|.:::.|...|...::|.:|.....:....:|...|...::...::|:|||.|..:.
Human   513 QSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSA 577

  Fly   541 DLSQFDKSRTESLQL---LIRSIDSTKKEGTRYDPKALSLDPSEALVL 585
            .|...|...:.||..   |:.|....::||:..:.:.|.|:|.|.|:|
Human   578 GLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	97/484 (20%)
SLC3A2	NP_001012680.1	SLC3A2_N	161..226	CDD:464983	3/6 (50%)
		AmyAc_SLC3A2	208..537	CDD:200483	95/478 (20%)
		DUF3459	520..625	CDD:432205	25/104 (24%)