Protein Alignment Mal-A8 and AMY2A

DIOPT Version :9

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_000690.1
• Gene: AMY2A / 279
• HGNCID: 477
• Length: 511
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 104/513 - (20%)
• Similarity: 174/513 - (33%)
• Gaps: 184/513 - (35%)

  Fly   104 GTLEDFRTLIKRAKELDLKIVLDFVPNH----------SSNESEWFLKSVKREKGYED-----YY 153
            |..::||.::.|...:.::|.:|.|.||          ||....:|      ..|..|     |.
Human    89 GNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYF------NPGSRDFPAVPYS 147

  Fly   154 VW--HDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKR 216
            .|  :|||..:.:|..|   |:     ..|.:..:.|....|        ||......|..::..
Human   148 GWDFNDGKCKTGSGDIE---NY-----NDATQVRDCRLTGLL--------DLALEKDYVRSKIAE 196

  Fly   217 VLRYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIE--NQPETID 279
            .:.:.::.||:|||.||          |...:|.::  .|..||...  |.:.:..  ::|
Human   197 YMNHLIDIGVAGFRLDA----------SKHMWPGDI--KAILDKLHN--LNSNWFPAGSKP---- 243

  Fly   280 MVYQWRTVLDDHKRIFGG---NSSVLLIETYSPAWFTMQFYGN-RSTEGAHLPFNFNLITVMEQ- 339
            .:||  .|:|     .||   .||              .::|| |.||   ..:...|.||:.:
Human   244 FIYQ--EVID-----LGGEPIKSS--------------DYFGNGRVTE---FKYGAKLGTVIRKW 284

  Fly   340 SGLSASNVQEAIDLWLKN-------MPAGRTPNWVLGNHDKRRAASRYGKENIDGMN-MLVMILP 396
            :|...|        :|||       :|:.|...:| .|||.:|.....|...:...: .|..:..
Human   285 NGEKMS--------YLKNWGEGWGFVPSDRALVFV-DNHDNQRGHGAGGASILTFWDARLYKMAV 340

  Fly   397 GVSVTYQGEEIGMTDGEISWE--------DTVDPW-GCNSNPNIYEQYTRDPERT---------- 442
            |..:.:   ..|.|....|:.        :.|:.| |..:|..:.::.|.:|:.|
Human   341 GFMLAH---PYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHR 402

  Fly   443 -----------------PF-QW--TGGTNAGFTNGS-----------------STWLPLAADYAT 470
                             || .|  .|.....|..|:                 .|.|| |..|..
Human   403 WRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLP-AGTYCD 466

  Fly   471 INVEKELSDDHSHLKIY-----KALVALRKSSKTLQNGSTKYQALSEDIFVVQRSLTK 523
            :....:::.:.:.:|||     ||..::..|              :||.|:...:.:|
Human   467 VISGDKINGNCTGIKIYVSDDGKAHFSISNS--------------AEDPFIAIHAESK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	100/494 (20%)
		trehalose_treC	33..585	CDD:274115	104/513 (20%)
		Malt_amylase_C	487..585	CDD:295440	8/42 (19%)
AMY2A	NP_000690.1	AmyAc_bac_euk_AmyA	25..416	CDD:200456	83/402 (21%)
		Aamy_C	422..510	CDD:214749	18/102 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930