Protein Alignment Mal-A8 and AMY1C

DIOPT Version :10

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001008220.1
• Gene: AMY1C / 278
• HGNCID: 476
• Length: 511
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 103/512 - (20%)
• Similarity: 170/512 - (33%)
• Gaps: 182/512 - (35%)

  Fly   104 GTLEDFRTLIKRAKELDLKIVLDFVPNH----------SSNESEWFLKSVKREKGYED-----YY 153
            |..::||.::.|...:.::|.:|.|.||          ||....:|      ..|..|     |.
Human    89 GNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYF------NPGSRDFPAVPYS 147

  Fly   154 VW--HDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKR 216
            .|  :|||..:.:|..|   |:     ..|.:..:.|....|        ||......|..::..
Human   148 GWDFNDGKCKTGSGDIE---NY-----NDATQVRDCRLSGLL--------DLALGKDYVRSKIAE 196

  Fly   217 VLRYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIENQPE-TIDM 280
            .:.:.::.||:|||.||          |...:|.::       |...|.|........|| :...
Human   197 YMNHLIDIGVAGFRIDA----------SKHMWPGDI-------KAILDKLHNLNSNWFPEGSKPF 244

  Fly   281 VYQWRTVLDDHKRIFGG---NSSVLLIETYSPAWFTMQFYGN-RSTEGAHLPFNFNLITVMEQ-S 340
            :||  .|:|     .||   .||              .::|| |.||   ..:...|.||:.: :
Human   245 IYQ--EVID-----LGGEPIKSS--------------DYFGNGRVTE---FKYGAKLGTVIRKWN 285

  Fly   341 GLSASNVQEAIDLWLKN-------MPAGRTPNWVLGNHDKRRAASRYGKENIDGMN-MLVMILPG 397
            |...|        :|||       ||:.|...:| .|||.:|.....|...:...: .|..:..|
Human   286 GEKMS--------YLKNWGEGWGFMPSDRALVFV-DNHDNQRGHGAGGASILTFWDARLYKMAVG 341

  Fly   398 VSVTY------------------QGEEIG-----MTDGEISWEDTVDP-------WGCNSNPNIY 432
            ..:.:                  .|:::.     ..|..::.|.|::|       |.|...   :
Human   342 FMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPPNDNGVTKEVTINPDTTCGNDWVCEHR---W 403

  Fly   433 EQ------YTRDPERTPF-QW--TGGTNAGFTNGS-----------------STWLPLAADYATI 471
            .|      :....:..|| .|  .|.....|..|:                 .|.|| |..|..:
Human   404 RQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLP-AGTYCDV 467

  Fly   472 NVEKELSDDHSHLKIY-----KALVALRKSSKTLQNGSTKYQALSEDIFVVQRSLTK 523
            ....:::.:.:.:|||     ||..::..|              :||.|:...:.:|
Human   468 ISGDKINGNCTGIKIYVSDDGKAHFSISNS--------------AEDPFIAIHAESK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	99/493 (20%)
AMY1C	NP_001008220.1	AmyAc_bac_euk_AmyA	25..416	CDD:200456	82/401 (20%)
		Aamy_C	422..510	CDD:214749	18/102 (18%)