DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mal-A8 and Amy1a

DIOPT Version :9

Sequence 1:	NP_610384.1	Gene:	Mal-A8 / 35830	FlyBaseID:	FBgn0033297	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_001010970.1	Gene:	Amy1a / 24203	RGDID:	2113	Length:	521	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	68/298 - (22%)
Similarity:	111/298 - (37%)	Gaps:	94/298 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 GTLEDFRTLIKRAKELDLKIVLDFVPNH----------SSNESEWFLKSVKREKG--YEDYYVWH 156
            |..::||.::.|...:.::|.:|.|.||          ||....:|..:.:...|  |.. :.::
  Rat    99 GNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAEAGQSSTCGSYFNPNNRDFPGVPYSG-FDFN 162

  Fly   157 DGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKRVLRYW 221
            |||..:.:|..|   |:     ..|.:..:.|....|        ||......|..::...:.:.
  Rat   163 DGKCKTGSGGIE---NY-----NDAAQVRDCRLSGLL--------DLALEKDYVRTKVADYMNHL 211

  Fly   222 LNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIE--NQPETIDMVYQW 284
            ::.||:|||.||          |...:|.::  .|..||...  |.|.:..  ::|    .:||
  Rat   212 IDIGVAGFRLDA----------SKHMWPGDI--KAVLDKLHN--LNTKWFSEGSKP----FIYQ- 257

  Fly   285 RTVLDDHKRIFGGNSSVLLIETYSPAWFTMQFYGN-RSTEGAHLPFNFNLITVMEQSGLSASNVQ 348
             .|:|     .||.           |..:.:::|| |.||     |.:         |.....|.
  Rat   258 -EVID-----LGGE-----------AVSSNEYFGNGRVTE-----FKY---------GAKLGKVL 291

  Fly   349 EAID----LWLKN-------MPAGRTPNWVLGNHDKRR 375
            ...|    .:|||       ||:.|...:| .|||.:|
  Rat   292 RKWDGEKMAYLKNWGEGWGFMPSDRALVFV-DNHDNQR 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	68/298 (23%)
		trehalose_treC	33..585	CDD:274115	68/298 (23%)
		Malt_amylase_C	487..585	CDD:295440
Amy1a	NP_001010970.1	AmyAc_bac_euk_AmyA	35..426	CDD:200456	68/298 (23%)
		AmyA	56..>325	CDD:223443	65/293 (22%)
		Aamy_C	432..520	CDD:214749
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337370
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830