Protein Alignment Mal-A8 and Slc3a1

DIOPT Version :9

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_033231.2
• Gene: Slc3a1 / 20532
• MGIID: 1195264
• Length: 685
• Species: Mus musculus
• Alignment Length: 604
• Identity: 219/604 - (36%)
• Similarity: 313/604 - (51%)
• Gaps: 61/604 - (10%)

  Fly     2 ELLSLLTL--LLLAIASNEACQVQSSSSETTKDWWQTAQFYQIYPRSFKDSDGDGIGDLNGITSK 64
            |:|..||:  :.|.|.:..|..|   .|....||||....||||||||||||.||.|||.||..|
Mouse    86 EILFWLTVVSVFLLIGATIAIIV---ISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEK 147

  Fly    65 LEYLKDLGVTAAWLSPIFKSPMVDFGYDISDFFDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVP 129
            |:|:..|.:...|::..:||.:.||.|.:.||.:|.|.:||::||..|:....:..||:::||:|
Mouse   148 LDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIP 212

  Fly   130 NHSSNESEWFLKSVKREKGYEDYYVWHD-GKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYL 193
            ||:|::..||..|..|...|.|||:||: ..||..|   .||.|||..:..|:|.::|||:|.|.
Mouse   213 NHTSDKHPWFQSSRTRSGKYTDYYIWHNCTHVNGVT---TPPNNWLSVYGNSSWHFDEVRKQCYF 274

  Fly   194 HQFAVQQPDLNYRNPLVVEQMKRVLRYWLNEGVSGFRCDALPPLFEV------VPDSDGQFPDEV 252
            |||..:|||||:|||.|.|::|.::.:||::||.||..||:..|.|.      :..:..|.||.|
Mouse   275 HQFLKEQPDLNFRNPAVQEEIKEIITFWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTV 339

  Fly   253 VSGATEDKEDRDYLTTTYIENQPETIDMVYQWRTVLDDHK------RIFGGNSSVLLIETYSPAW 311
                |...|.....|||.:...    |:|..:|..::.:.      |..|..:|...||.
Mouse   340 ----THYSELYHDFTTTQVGMH----DIVRDFRQTMNQYSREPGRYRFMGAEASAESIER----- 391

  Fly   312 FTMQFYGNRSTEGAHLPFNFNLITVMEQSGLSASNVQEAIDLWLKNMPAGRTPNWVLGNHDKRRA 376
             ||.:||....:.|..|||....|:   ..||...|.|.|..|::|||.|:.|||:.|..:..|.
Mouse   392 -TMMYYGLPFIQEADFPFNKYFTTI---GTLSGHTVYEVITSWMENMPEGKWPNWMTGGPETPRL 452

  Fly   377 ASRYGKENIDGMNMLVMILPGVSVTYQGEEIGMTDGEISWEDTVDPWGCNSNPNIYEQY--TRDP 439
            .||.|.|.::.|:||:..|||..:||.||||||.|..::              |..|.|  |...
Mouse   453 TSRVGSEYVNAMHMLLFTLPGTPITYYGEEIGMGDISVT--------------NFNESYDSTTLV 503

  Fly   440 ERTPFQWTGGTNAGFTNGSSTWLPLAADYATINVEKELSDDHSHLKIYKALVALRKSSKTLQNGS 504
            .::|.||...:|||||..:.||||..:||.|:||:.:.:...|.|::|:.|..|..:...|..|
Mouse   504 SKSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLSRG- 567

  Fly   505 TKYQALSED--IFVVQRSLTKSATIVLVI-NFGSVAKTVDLSQFDKSRTESLQLLIRSIDSTKKE 566
             .:..|.:|  ..|..|.|.....:.||: |||..:..::|..........|:  ||...::..:
Mouse   568 -WFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELR--IRLSTNSASK 629

  Fly   567 GTRYDPKALSLDPSEALVL 585
            |:..|.:|:||:..|.|||
Mouse   630 GSAVDTRAISLEKGEGLVL 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	187/490 (38%)
		trehalose_treC	33..585	CDD:274115	207/569 (36%)
		Malt_amylase_C	487..585	CDD:295440	26/100 (26%)
Slc3a1	NP_033231.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		SLC3A2_N	64..122	CDD:292647	13/38 (34%)
		AmyAc_SLC3A1	115..568	CDD:200494	187/488 (38%)
		trehalose_treC	116..604	CDD:274115	196/523 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833815
Domainoid	1	1.000	276	1.000	Domainoid score	I1723
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2073
Isobase	1	0.950	-	0.709012	Normalized mean entropy	S2995
OMA	1	1.010	-	-		QHG53234
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000282
OrthoInspector	1	1.000	-	-		otm42374
orthoMCL	1	0.900	-	-		OOG6_100402
Panther	1	1.100	-	-	O	PTHR10357
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.750