Protein Alignment Mal-A8 and Slc3a2

DIOPT Version :10

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001154885.1
• Gene: Slc3a2 / 17254
• MGIID: 96955
• Length: 565
• Species: Mus musculus
• Alignment Length: 587
• Identity: 125/587 - (21%)
• Similarity: 202/587 - (34%)
• Gaps: 211/587 - (35%)

  Fly    33 WWQTAQFYQIYP-RSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPMVDFGYDISDF 96
            ||.....|:|.. ::|...|..||.   |:.|.||||..|.|....|.||.|:...:.  :.:|.
Mouse   150 WWHKGALYRIGDLQAFVGRDAGGIA---GLKSHLEYLSTLKVKGLVLGPIHKNQKDEI--NETDL 209

  Fly    97 FDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKSVKREKGYEDYYVWHDGKVN 161
            ..|.|..|:.|||:.|::.||:..:.|:||..||: ..::.|||.:
Mouse   210 KQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNY-QGQNAWFLPA------------------- 254

  Fly   162 STTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKRVLRYWLNEGV 226
                                                  |.|      :|..:||..|..||.:||
Mouse   255 --------------------------------------QAD------IVATKMKEALSSWLQDGV 275

  Fly   227 SGFRCDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIENQPETIDMVY--QWRTVL- 288
            .||                 ||.|                 ...:.|.|     :|  :|:.:.
Mouse   276 DGF-----------------QFRD-----------------VGKLMNAP-----LYLAEWQNITK 301

  Fly   289 ---DDHKRIFGGNSS-----VLLIETYSPAWFTMQFYGNRSTEGAHLPFNFNLIT---------- 335
               :|...|.|..||     |.::|:.|....|..:..|.:..|....   :|:|
Mouse   302 NLSEDRLLIAGTESSDLQQIVNILESTSDLLLTSSYLSNSTFTGERTE---SLVTRFLNATGSQW 363

  Fly   336 ---VMEQSGLSASNVQEAIDLWLKNMPAGRTPNWVLGNHDKRRAASRYGKENIDGMNMLVMILPG 397
               .:.|:||.|..:                |:.:|..:                 .:|:..|||
Mouse   364 CSWSVSQAGLLADFI----------------PDHLLRLY-----------------QLLLFTLPG 395

  Fly   398 VSVTYQGEEIGMTDGEISWEDTVDPWGCNSNPNIYEQYTRDPERTPFQ-WTGGTNAGFTNGSSTW 461
            ..|...|:|:|: .|.:..:                     |.:.|.. |         |.||.:
Mouse   396 TPVFSYGDELGL-QGALPGQ---------------------PAKAPLMPW---------NESSIF 429

  Fly   462 -LPLAADYATINVEKELSDDHSHLKIYKALVALRKSSKTLQNGSTKYQALSEDIFVVQRSLTKSA 525
             :|.... ..:.|:.:..|..|.|..::.|..||...::|.:|.....:.|.|:|...|...::.
Mouse   430 HIPRPVS-LNMTVKGQNEDPGSLLTQFRRLSDLRGKERSLLHGDFHALSSSPDLFSYIRHWDQNE 493

  Fly   526 TIVLVINFGSVAKTVDLSQFDK----SRTESLQLLIRSIDS---TKKEGTRYDPKALSLDPSEAL 583
            ..::|:||....::..|...:.    |...|.:||: |.||   :::|.|....:.|||:|.|.|
Mouse   494 RYLVVLNFRDSGRSARLGASNLPAGISLPASAKLLL-STDSARQSREEDTSLKLENLSLNPYEGL 557

  Fly   584 VL 585
            :|
Mouse   558 LL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	101/499 (20%)
Slc3a2	NP_001154885.1	SLC3A2_N	84..157	CDD:464983	2/6 (33%)
		AmyAc_family	139..468	CDD:476817	99/493 (20%)