Protein Alignment Mal-A8 and CD98hc

DIOPT Version :10

• Sequence 1: NP_610384.1
• Gene: Mal-A8 / 35830
• FlyBaseID: FBgn0033297
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_311140.4
• Gene: CD98hc / 1272256
• VectorBaseID: AGAMI1_004569
• Length: 642
• Species: Anopheles gambiae
• Alignment Length: 607
• Identity: 137/607 - (22%)
• Similarity: 224/607 - (36%)
• Gaps: 191/607 - (31%)

  Fly    22 VQSSSSE-TTKDWWQTAQFYQIYPRSFKDSDGDGIGD--------LNGITSK--LEYLKD-LGVT 74
            |:.|.:| |.||  :.|| .::..:.....:||...|        |.|:|.:  ::|..| ..|.
Mosquito    85 VEPSGAEPTEKD--KLAQ-KEVEVKFIPSQNGDARIDMELESQQALTGMTKEELMKYANDPFWVR 146

  Fly    75 AAWL---------------------------SPI-----FKSPMVDFGYDISDFFDIQPE---YG 104
            ..||                           :|:     .:.|:|:...: ..|.|..||   ||
Mosquito   147 LRWLLFVLFWALWGAMLLGSFYIIYDAPKCAAPVPLSWWQEGPLVELDGE-RQFADQLPEVERYG 210

  Fly   105 TL-------EDFRTLIKRA------KEL-------DLKIVLDFVPNHSSNESEWFLKSV-KREKG 148
            ..       .|...|::.|      |:|       |:|:|:|..||:.:.|...|.::: |.:..
Mosquito   211 AKGVIYRLPADETYLVETAAVQGKLKQLVSTFGTKDVKVVVDITPNYVTKEDALFQEALQKPDSA 275

  Fly   149 YEDYYVWHDGKVNSTTGKREPPTNWLQYF-RGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVE 212
            ....:||.:..:.        |.|||... .||||: |....||.|.||...:.||....|...:
Mosquito   276 AHSAFVWREAGMK--------PPNWLSIAEEGSAWK-NASNNQYVLSQFGADRYDLQLGEPAARD 331

  Fly   213 QMKRVLRYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATE-DKE----DRDYLT---TT 269
            ::|..|:..|.:||.|.|   |.....::.:.||  .||......| ||.    |..:.|   ||
Mosquito   332 KLKATLKALLGQGVRGVR---LANAKHLLINRDG--GDEAPMNLEEADKSLTHTDYGFWTHKETT 391

  Fly   270 YIENQ----PETIDMVYQ------WRTVLDDHKR--IFGGNSSVLLIETYSPAWFTMQFYGNRST 322
            |.|..    .|.:::|::      :.:|.:|..|  :|..|.:   ::..:|      .|||
Mosquito   392 YREGLGELFRELVELVHEQTDGEGFLSVTEDILRPEVFAVNGT---LQMDAP------LYGN--- 444

  Fly   323 EGAHLPFNFNLITVMEQSGLS-ASNVQEAIDLWLKNMP--------AGRTPNWVLGNHDKRR--- 375
                  ..|:|   .|.||.. |..::..|:...:.:.        ||....|:...:|:..
Mosquito   445 ------IEFDL---REGSGPDVARKLRHDIENAYRTISEYAVVASGAGSGKPWLQLRYDRASLEH 500

  Fly   376 -AASRYGKENIDGMNMLVMILPGVSVTYQGEEIGMTDGEISWE--DTVDPWGCNSNP-------N 430
             .||.|        .:...:||||.|.....   :|.|.:|.|  :|::.:  .:.|       |
Mosquito   501 VPASEY--------TVFHFLLPGVPVFPLDV---LTRGNVSSESVETLEKF--RATPSFQHGLFN 552

  Fly   431 IYEQ-------YTR----DP------------ERTPFQWTGGTNAGFTNGSSTWLPLAADYA--T 470
            .|..       |||    :|            ::|.|.::|....|   ...|.:..:.:||  .
Mosquito   553 AYTDANASAIAYTRLKSGNPGYFVVLNLASTDQKTTFDFSGIDGIG---SELTVVLTSQNYAVPN 614

  Fly   471 INVEKELSDDHSHLKIYKALVA 492
            :.|:.::..|...|....||:|
Mosquito   615 VGVKTKVPVDAVPLSPKSALIA 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	133/598 (22%)
CD98hc	XP_311140.4	AmyAc_maltase-like	120..613	CDD:200468	120/544 (22%)