Protein Alignment Mal-A7 and IMA4

DIOPT Version :10

• Sequence 1: NP_610383.1
• Gene: Mal-A7 / 35829
• FlyBaseID: FBgn0033296
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_012314.1
• Gene: IMA4 / 853235
• SGDID: S000003757
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 598
• Identity: 181/598 - (30%)
• Similarity: 270/598 - (45%)
• Gaps: 108/598 - (18%)

  Fly    20 AHPSWSCETTTSTTVTKDWWENAQFYQIYPRSFMDSDGDGIGDLNGITSKLEYLKDLGVTAAWLS 84
            |||    ||...      ||:.|..|||||.||.||:.||.||:.||.|||||:|:||..|.|:|
Yeast     6 AHP----ETEPK------WWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWIS 60

  Fly    85 PIFTSPMVDFGYDISDFFDIQPEYGTLDDFRALIKRANELDLKIILDFVPNHSSDENSWFVKS-V 148
            |.:.||..|.||||:::..:.|.|||.:|..|||::.::|.:|.|.|.|.||.|.|:.||.:| .
Yeast    61 PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRS 125

  Fly   149 NREKGYEDYYVWHDGRVNATTGGREPPSNWLQAFRGSAWEWNEKRQQYYLHQFAVQQADLNYRNP 213
            ::.....|::.|...:.....|...||:||...|.||||.::||.|::||..|...|.|||:.|
Yeast   126 SKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWEN- 189

  Fly   214 LVVEQMKRVL-----RYWLDLGVAGFRCDAVPVLFEIEPDADGQYADEELSGLTD----DVDDRK 269
               |..::.:     .||||.||.|||.| |..|:            .:::||.|    |.:.:.
Yeast   190 ---EDCRKAIYESAVGYWLDHGVDGFRID-VGSLY------------SKVAGLPDAPVIDENSKW 238

  Fly   270 YLKSDLIENRPETIDMAYQWRVVMDDY--QRIHGGETRVLLIETYAPPAYTMQFYGNRSTAGAHL 332
            .|......|.|.    .:::...|:.:  .|:..|...:.:.|.......|.:.|.:.|......
Yeast   239 QLSDPFTMNGPR----IHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSE 299

  Fly   333 PFNFNLITVLASDGVSAGSIKTAVDNWLDNLP-----AGRTANW---VIGNHDQRRAASRYG--- 386
            .|||:...|..|.......|...:.:|...|.     ...|..|   .:.||||.|:.:|:|
Yeast   300 LFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDS 364

  Fly   387 ----TANADAMNMLVMVLPGASVTYQGEELGMTDGEI---SW--EDTQDPAACNSNSDIYEQ--- 439
                ..:...:::|::.|.|....|||:||    |||   :|  |..:|....|:...|.|:
Yeast   365 PKNRVISGKLLSVLLVSLSGTLYVYQGQEL----GEINFKNWPIEKYEDVEVRNNYDAIKEEHGE 425

  Fly   440 --------------FTRDPSRTPFQWT-NGTNAGFS-TASKTWLPLAADY-QTLNVETEAAAQRS 487
                          .:||.:|||.||: ...||||| ..:|.|..|...: :.:|.|.|:....|
Yeast   426 NSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNS 490

  Fly   488 HLKIYKALVELRKSSLPLQNGSTKYGVVGENVFV--------VKRYISGSASIIYVANFASKGVT 544
            .|..:|..:..||:...:    |.||...|.:.:        .|:|  .:.::....||:|..:
Yeast   491 VLNFWKEALRFRKAHKDI----TVYGYDFEFIDLDNKKLFSFTKKY--DNKTLFAALNFSSDSI- 548

  Fly   545 VDLYEFDKTLPTH 557
                  |.|:|.:
Yeast   549 ------DFTIPNN 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A7	NP_610383.1	AmyAc_maltase	36..511	CDD:200467	164/526 (31%)
IMA4	NP_012314.1	AmyAc_SI_OligoGlu_DGase	16..503	CDD:200472	160/511 (31%)
		Malt_amylase_C	514..585	CDD:435493	9/51 (18%)