DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mal-A7 and SBE2.1

DIOPT Version :9

Sequence 1:	NP_001286198.1	Gene:	Mal-A7 / 35829	FlyBaseID:	FBgn0033296	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_181180.1	Gene:	SBE2.1 / 818212	AraportID:	AT2G36390	Length:	858	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	111/542 - (20%)
Similarity:	180/542 - (33%)	Gaps:	201/542 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LEYLKDLGVTAAWLSPI-----FTSPMVDFGYDISDFFDIQPEYGTLDDFRALIKRANELDLKII 129
            |..:|.||..|..:..|     :.|    |||.:::||.....:||.||.::||.:|:||.|.::
plant   353 LPRIKKLGYNAVQIMAIQEHAYYAS----FGYHVTNFFAPSSRFGTPDDLKSLIDKAHELGLVVL 413

  Fly   130 LDFVPNHSSDENSWFVKSVNREKGYEDYYVWHDGRVNATTGGREPPSNWLQAFRGSAWEWNEKRQ 194
            :|.|.:|:|...   :..::...|.:..| :|.|.                  ||..|.|:.:.
plant   414 MDIVHSHASKNT---LDGLDMFDGTDGQY-FHSGS------------------RGYHWMWDSRL- 455

  Fly   195 QYYLHQFAVQQADLNYRNPLVVEQMKRVLRYWL-DLGVAGFRCDAVPVLF----EIEPDADGQYA 254
                         .||.:..|:..:....|:|| :....|||.|.|..:.    .::.:..|.|
plant   456 -------------FNYGSWEVLRYLLSNARWWLEEYKFDGFRFDGVTSMMYTHHGLQVEFTGNY- 506

  Fly   255 DEELSGLTDDVDDRKYLK--SDLIEN-RPETIDMAYQWRVVMDDYQRIHGGETRVLLIETYAPPA 316
             .|..|.:.|||...||.  :|||.. .||.|       ||.:|...:               ||
plant   507 -NEYFGYSTDVDAVVYLMLVNDLIHGLYPEAI-------VVGEDVSGM---------------PA 548

  Fly   317 YTMQFYGNRSTAGAHLPFNFNLITVLASDGVSAGSIKTAVDNWLDNLPAGRTANWVIG------- 374
            :.:      ......:.|::.|...:|             |.|::.|.. |..:|.:|
plant   549 FCV------PVEDGGVGFDYRLHMAVA-------------DKWIELLKK-RDEDWQVGDITFTLT 593

  Fly   375 -------------NHDQ------------------------RRAASRY--GTANADAMNMLVMVL 400
                         :|||                        |:|..|.  |.|....:.::.|.|
plant   594 NRRWGEKCVVYAESHDQALVGDKTIAFWLMDKDMYDFMAVDRQATPRVDRGIALHKMIRLITMGL 658

  Fly   401 PGAS-VTYQGEELGMTDGEISWEDTQDPAACNSNSDIYEQFTRDPSRTP-FQWTNGTNAGFSTAS 463
            .|.. :.:.|.|.|..:    |.|                |.|.....| .:...|.|..:....
plant   659 GGEGYLNFMGNEFGHPE----WID----------------FPRTDQHLPDGRVIAGNNGSYDKCR 703

  Fly   464 KTWLPLAADYQTLNVETEAAAQRSHLKIYKALVELRKSSLPLQNGSTKYGVV------------G 516
            :.:....|:|..                |..|.|..::   :||....||.:            |
plant   704 RRFDLGDAEYLR----------------YHGLQEFDRA---MQNLEETYGFMTSEHQYISRKDEG 749

  Fly   517 ENVFVVKRYISGSASIIYVANF 538
            :.|.|.:|     .::::|.||
plant   750 DRVIVFER-----GNLLFVFNF 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A7	NP_001286198.1	AmyAc_maltase	36..511	CDD:200467	102/501 (20%)
Mal-A7	NP_001286198.1	trehalose_treC	38..547	CDD:274115	111/542 (20%)
SBE2.1	NP_181180.1	PLN02447	150..830	CDD:215246	111/542 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910