Protein Alignment Mal-A7 and SLC3A2

DIOPT Version :9

• Sequence 1: NP_001286198.1
• Gene: Mal-A7 / 35829
• FlyBaseID: FBgn0033296
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001012680.1
• Gene: SLC3A2 / 6520
• HGNCID: 11026
• Length: 631
• Species: Homo sapiens
• Alignment Length: 610
• Identity: 122/610 - (20%)
• Similarity: 198/610 - (32%)
• Gaps: 201/610 - (32%)

  Fly     6 LDHFGLLVCGLVILAHPSWSCETTTSTTVTKDWWENAQFYQIYPRSFMDSDGDGIGDLNGITSKL 70
            |...|:|...:||:.... .|....:    :.||.....|:|  .......|.|.|:|.|:..:|
Human   192 LGWLGMLAGAVVIIVRAP-RCRELPA----QKWWHTGALYRI--GDLQAFQGHGAGNLAGLKGRL 249

  Fly    71 EYLKDLGVTAAWLSPIFTSPMVDFGYDISDFFDIQPEYGTLDDFRALIKRANELDLKIILDFVPN 135
            :||..|.|....|.||..:...|...  :|...|.|.:|:.:||.:|::.|.:..:::|||..||
Human   250 DYLSSLKVKGLVLGPIHKNQKDDVAQ--TDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPN 312

  Fly   136 HSSDENSWFVKSVNREKGYEDYYVWHDGRVNATTGGREPPSNWLQAFRGSAWEWNEKRQQYYLHQ 200
            :.. |||||...|:
Human   313 YRG-ENSWFSTQVD--------------------------------------------------- 325

  Fly   201 FAVQQADLNYRNPLVVEQMKRVLRYWLDLGVAGFRC-------DAVPVLFEIEPDADGQYADEEL 258
                         .|..::|..|.:||..||.||:.       ||...|.|.:....|...|..|
Human   326 -------------TVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLL 377

  Fly   259 SGLTDDVDDRKYLKSDLIENRPETIDMAYQWRVVMDDYQRIHGGETRVLLIETYAPPAYTMQFYG 323
            ...|:..|.::.|  .|:|:..:                        :||..:|
Human   378 IAGTNSSDLQQIL--SLLESNKD------------------------LLLTSSY----------- 405

  Fly   324 NRSTAGAHLPFNFNLITVLASDGVSAGSIKTAVDNWLDNLPAGRTANWVIGNHDQRRAASRYGTA 388
                              |:..|.:....|:.|..:| |....|..:|.:   .|.|..:.:..|
Human   406 ------------------LSDSGSTGEHTKSLVTQYL-NATGNRWCSWSL---SQARLLTSFLPA 448

  Fly   389 NADAM-NMLVMVLPGASVTYQGEELGMTDGEIS----------WEDT---QDPAACNSNSDIYEQ 439
            ....: .:::..|||..|...|:|:|:....:.          |:::   ..|.|.::|..:..|
Human   449 QLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQ 513

  Fly   440 FTRDPSRTPFQWTNGTNAGFSTASKTWLPLAADYQTLNVETEAAAQRSHLKIYKALVELRKSSLP 504
             :.||.                                         |.|.:::.|.:.|.....
Human   514 -SEDPG-----------------------------------------SLLSLFRRLSDQRSKERS 536

  Fly   505 LQNGSTKYGVVGENVFVVKRYISGSASIIYVANFASKGVTVDLYEFD----KTLPTHLTLLIRSL 565
            |.:|.......|..:|...|:...:...:.|.||...|::..|...|    .:||....||: |.
Human   537 LLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLL-ST 600

  Fly   566 QSSKAEGSQFEVTGLSLAAGEALVL 590
            |..:.|||..|:..|.|...|.|:|
Human   601 QPGREEGSPLELERLKLEPHEGLLL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A7	NP_001286198.1	AmyAc_maltase	36..511	CDD:200467	92/495 (19%)
		trehalose_treC	38..547	CDD:274115	99/529 (19%)
SLC3A2	NP_001012680.1	SLC3A2_N	161..225	CDD:292647	8/37 (22%)
		AmyAc_SLC3A2	208..537	CDD:200483	91/503 (18%)
		AmyA	238..597	CDD:223443	98/526 (19%)
		DUF3459	520..625	CDD:288769	28/105 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143604
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.712175	Normalized mean entropy	S6632
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R680
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.730