DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mal-A7 and Amy-p

DIOPT Version :9

Sequence 1:	NP_001286198.1	Gene:	Mal-A7 / 35829	FlyBaseID:	FBgn0033296	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001286518.1	Gene:	Amy-p / 47764	FlyBaseID:	FBgn0000079	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	582	Identity:	127/582 - (21%)
Similarity:	187/582 - (32%)	Gaps:	192/582 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 NAQFYQIYPRSFMDSDGDGIGDL-----NGITSKLE-YLKDLGVTAAWLSPIFTSPMVDFG---- 95
            ||||...|.     |...|:..|     :.|.::.| :|...|.....:||:..:.:.|..
  Fly    17 NAQFDTNYA-----SGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDSRPWWE 76

  Fly    96 --YDISDFFDIQPEYGTLDDFRALIKRANELDLKIILDFVPNHSSDENSWFVKSVNREKGYEDYY 158
              ..||  :.::...|..:.|.:::||.|.:.::..:|.|.||.:
  Fly    77 RYQPIS--YKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMA-------------------- 119

  Fly   159 VWHDGRVNATTGGREPPSNWLQAFRGSAW---------------EWNEKRQQYYLHQFAVQQADL 208
              .||....|.|....||:  :::.|..:               :.||.|     :...|...||
  Fly   120 --ADGGTYGTGGSTASPSS--KSYPGVPYSSLDFNPTCAISNYNDANEVR-----NCELVGLRDL 175

  Fly   209 NYRNPLVVEQMKRVLRYWLDLGVAGFRCDAVPVLFEIEPDADGQYADEELSGLTDDVDDRKYLKS 273
            |..|..|.:::...|.:.:||||||||.||...::    .||.......|..|..|.......|:
  Fly   176 NQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMW----PADLAVIYGRLKNLNTDHGFASGSKA 236

  Fly   274 DLIENRPETIDMAYQWRVVMDDYQRIHGGETRVLLIETYAPPAYTMQFYGNRSTAGAHLPFNFNL 338
            .:::   |.|||               ||       |..:...||        ..||...|..
  Fly   237 YIVQ---EVIDM---------------GG-------EAISKSEYT--------GLGAITEFRH-- 266

  Fly   339 ITVLASDGVSAGSIKTAVD------NWLDNLPAGRTANW----------VIGNHDQRRAASRYGT 387
                 ||  |.|.:....|      ||       .|| |          .:.|||.:|.   :|.
  Fly   267 -----SD--SIGKVFRGKDQLQYLTNW-------GTA-WGFAASDRSLVFVDNHDNQRG---HGA 313

  Fly   388 ANADAMNMLV-------------------MVLPGASVTYQGEELGMTDGEISWEDTQDPAACNSN 433
            ..||.:...|                   .|:...|.|...:....|||    .:...|...:.|
  Fly   314 GGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQGPPTTDG----HNIASPIFNSDN 374

  Fly   434 S------------DIYEQ--FTRDPSRTPFQ--WTNGTN-AGFSTASKTWLPLAADYQTLNVETE 481
            |            .||..  |.........|  |.||:| ..||..|:.::....|...||...:
  Fly   375 SCSGGWVCEHRWRQIYNMVAFRNTVGLDEIQNWWDNGSNQISFSRGSRGFVAFNNDNYDLNSSLQ 439

  Fly   482 AAAQRSHLKIYKALVELRKSSLPLQNGSTKYGVVGENVFVVKRYISGSASIIYVANFASKGV 543
            ......   .|..::...||      ||:   ..|:.|.|..   .|.|| ||:.:....||
  Fly   440 TGLPAG---TYCDVISGSKS------GSS---CTGKTVTVGS---DGRAS-IYIGSSEDDGV 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A7	NP_001286198.1	AmyAc_maltase	36..511	CDD:200467	117/548 (21%)
Mal-A7	NP_001286198.1	trehalose_treC	38..547	CDD:274115	127/582 (22%)
Amy-p	NP_001286518.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	95/462 (21%)
		Alpha-amylase	54..342	CDD:278554	78/375 (21%)
		Aamy_C	405..493	CDD:214749	26/97 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443609
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830