Protein Alignment Mal-A5 and MAL12

DIOPT Version :10

• Sequence 1: NP_610382.2
• Gene: Mal-A5 / 35828
• FlyBaseID: FBgn0050359
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_011808.3
• Gene: MAL12 / 853209
• SGDID: S000003524
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 586
• Identity: 183/586 - (31%)
• Similarity: 262/586 - (44%)
• Gaps: 118/586 - (20%)

  Fly    35 IGDH-GADLKWWQTAAFYQIYPRSFKDSNGDGVGDLNGIAEQLPYLKELGITATWLSPIFTSPMA 98
            |.|| ..:.|||:.|..|||||.||||||.||.|||.||..:|.|:|:||:.|.|:.|.:.||..
Yeast     3 ISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQ 67

  Fly    99 DFGYDIANFTEIAPIFGTMADFEHLMEVAKKLDIKIILDFVPNHSSDECEWFR--RSAARDPEFK 161
            |.||||:|:.::.|.:||..|...|::...||.:|.|.|.|.||.|.|.|||:  ||:..:|: :
Yeast    68 DMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPK-R 131

  Fly   162 DFYVWHP--GRMENGNRHPPSNWISVFRGSAWQWHEGRQEFYLHQFVKKQPDLNYRNPKVRETM- 223
            |::.|.|  |....|...||:||.|.|.||||.:.|...||||..|..:|.|||:.|...|..:
Yeast   132 DWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIF 196

  Fly   224 SNVLRFWLGKGVAGFRIDAV------PHVFEIAPD----NQNQYRDEPRNDWDNDPEDYGYLQ-- 276
            .:.:.|||..||.|||||..      |.:    ||    ::......|.....|.|..:.|.|
Yeast   197 ESAVGFWLDHGVDGFRIDTAGLYSKRPGL----PDSPIFDKTSKLQHPNWGSHNGPRIHEYHQEL 257

  Fly   277 HIYTKDQPETIDLVYSWRAVLDAHQREHGGEDRILMAET----------------------YSPI 319
            |.:.|::      |...|.::...:..||.::.:..:..                      |:.:
Yeast   258 HRFMKNR------VKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIV 316

  Fly   320 DIVMQYYGNATAEGAQLPFNFLLISELSNSSNAHAYEGTVLKWLQHMPKGRTANWVLGNHDQPRV 384
            ...::.:..|.|.      |||.|:            ||. .|         |...:.||||.|.
Yeast   317 PFTLKQWKEAIAS------NFLFIN------------GTD-SW---------ATTYIENHDQARS 353

  Fly   385 GSRLGRDRV-------DMLNMLTATLPGASVTYQGEELGMTNV--W-ISWKDTVDPSACNTNPSI 439
            .:|...|..       .:|.:|..:|.|....|||:|:|..|.  | |...:.||   ...|..|
Yeast   354 ITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVD---VKNNYEI 415

  Fly   440 YEQ------------------YSRDPERTPFQWT-DAQDAGFSNAS-KTWLPIAVDYKE-VNVEQ 483
            .::                  .|||..|||..|| |..:|||:... |.|..:...::: :||||
Yeast   416 IKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQ 480

  Fly   484 ERQKPLSHLNVFKQLWQLRKQSQTLKRGETEVKAL---SDAVLAVKRYLERDSTYLTLLNIYDGV 545
            |.:...|.||.:|:..|.||:.:.|.....:.:.:   ||.:.:..:..| |.|....|| :.|.
Yeast   481 ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYE-DKTLFAALN-FSGE 543

  Fly   546 E 546
            |
Yeast   544 E 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A5	NP_610382.2	AmyAc_maltase	41..514	CDD:200467	171/542 (32%)
MAL12	NP_011808.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	166/527 (31%)
		Malt_amylase_C	511..583	CDD:435493	9/36 (25%)