Protein Alignment Mal-A5 and slc3a1

DIOPT Version :10

• Sequence 1: NP_610382.2
• Gene: Mal-A5 / 35828
• FlyBaseID: FBgn0050359
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_021336428.1
• Gene: slc3a1 / 557757
• ZFINID: ZDB-GENE-090313-225
• Length: 674
• Species: Danio rerio
• Alignment Length: 605
• Identity: 242/605 - (40%)
• Similarity: 344/605 - (56%)
• Gaps: 69/605 - (11%)

  Fly    42 LKWWQTAAFYQIYPRSFKDSNGDGVGDLNGIAEQLPYLKELGITATWLSPIFTSPMADFGYDIAN 106
            :.|||.:..||:|||||||||.||||||.||.|:|.:.:.|.|.|.|:||.:.|||.|||||:.:
Zfish   105 MSWWQLSPIYQVYPRSFKDSNADGVGDLRGIKEKLSHFEYLNIKAIWISPFYKSPMRDFGYDVED 169

  Fly   107 FTEIAPIFGTMADFEHLMEVAKKLDIKIILDFVPNHSSDECEWFRRSAARDPEFKDFYVWHPGRM 171
            |.::.|:||||.||:.|:.......:|:|:|::|||:||:..||:.|......:.|:|:|
Zfish   170 FRDVDPLFGTMEDFDDLLTSMHDKGLKLIMDYIPNHTSDKHVWFQLSRNYTEPYTDYYIW----- 229

  Fly   172 EN--GNRHPPSNWISVFRGSAWQWHEGRQEFYLHQFVKKQPDLNYRNPKVRETMSNVLRFWLGKG 234
            .|  .::| |:||:|||..|.|::.|.||:.|.|||:|:|||||||||.|.:.|::::.|||.||
Zfish   230 VNCTADKH-PNNWVSVFGNSTWEYDEIRQQCYFHQFLKEQPDLNYRNPLVLQEMTDIIHFWLKKG 293

  Fly   235 VAGFRIDAVPHVFEIAPDNQNQYRDEPRNDWDNDPE--DYGY-LQHIYTKDQPETIDLVYSWRAV 296
            |.|||:|||.|:.|     ....||||:.:.|.||.  |..: |.|.||..|....:::..||..
Zfish   294 VDGFRMDAVKHMLE-----ATHLRDEPQVNPDQDPSTVDTEFELYHDYTYTQAGLHEILTDWRIQ 353

  Fly   297 LDAHQREHGGEDRILMAET--YSPIDIVMQYYGNATAEGAQLPFNFLLISELSNSSNAHAYEGTV 359
            :|.:.|| .|..|.::.|:  |..||..|:|||...|:.:..||||.|:....|.|..:| :..|
Zfish   354 MDTYSRE-PGRYRFMVMESYDYEEIDKTMRYYGTNYAKESDFPFNFYLLDLPDNLSGNYA-KSIV 416

  Fly   360 LKWLQHMPKGRTANWVLGNHDQPRVGSRLGRDRVDMLNMLTATLPGASVTYQGEELGMTNVWISW 424
            .:|:.:||||:..|||:||||:||:||..|::.|..||||..||||...||.|||:||.:|.||
Zfish   417 ERWMSNMPKGKWPNWVVGNHDKPRIGSSAGKEYVRALNMLLLTLPGTPTTYYGEEIGMVDVNIS- 480

  Fly   425 KDTVDPSACNTNPSIYEQYSRDPERTPFQWTDAQDAGFSNA-SKTWLPIAVDYKEVNVEQERQKP 488
              .:...|...:||    .||||:|||.||.:..:||||.: :.|||.||.||:.||||.::...
Zfish   481 --VIQDPAGQYDPS----KSRDPQRTPMQWNNELNAGFSESLNGTWLDIASDYRTVNVEVQQDDT 539

  Fly   489 LSHLNVFKQLWQLRKQSQTLKRG-----ETEVKALSDAVLAVKRYLERDST-YLTLLNIYDGVET 547
            .|.::.::.|..||..:..|.||     ..:|.     |.|..|.|:..|. :|.:||.  |.||
Zfish   540 SSTISQYRALSLLRSSNVILSRGWFCYVWNDVN-----VFAYLRELDGLSKGFLVVLNF--GKET 597

  Fly   548 INLLQSFPDLPPQLKVVVVTERSQVKVGDLVNSTSLQLQPK--------DSLVLQTTSSYYSYAT 604
            ...|.|..:||..|.:.:.||.        :..|..   ||        ..|:|:.:|| ..:..
Zfish   598 TTDLSSVKELPDSLTLHLSTES--------ITQTEF---PKSRIPTSQGQGLLLEYSSS-QKFHL 650

  Fly   605 NGETR--------FLPVLGV 616
            |.:::        :||.|.:
Zfish   651 NHQSQCYVSEKACYLPALDI 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A5	NP_610382.2	AmyAc_maltase	41..514	CDD:200467	212/484 (44%)
slc3a1	XP_021336428.1	SLC3A2_N	55..114	CDD:464983	3/8 (38%)
		AmyAc_SLC3A1	106..563	CDD:200494	211/476 (44%)