Protein Alignment Mal-A5 and CD98hc

DIOPT Version :10

• Sequence 1: NP_610382.2
• Gene: Mal-A5 / 35828
• FlyBaseID: FBgn0050359
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 132/637 - (20%)
• Similarity: 217/637 - (34%)
• Gaps: 202/637 - (31%)

  Fly     2 IKYRLIAFL------------AVLLQLHCPTLG--QPYPNY----HADFVGIGDHGADLKWWQTA 48
            ::.|.|.|:            |:|:.:..|...  ||.|.|    ||.|..:          :|.
  Fly   142 VRLRWIFFVCFWAIWVGMLVGAILIIIGAPKCAAPQPLPWYKRGPHAKFASV----------ETC 196

  Fly    49 AFYQIYPRSFKDSNGDGVGDLNGIAEQLPYLKELGITATWLSPIFTSPMADFGYDIANFTEIAPI 113
            .                       .|.:...|:| ::|   ..|:..|.| ..||:.. .|:.
  Fly   197 R-----------------------PEDVQVAKKL-VSA---GAIYELPAA-LTYDVKK-PEVE-- 230

  Fly   114 FGTMADFEHLMEVAKKLDIKIILDFVPNHSSDECEWFRRSAARDPEFKDFYVWHPGRMENGNRHP 178
                ...:||:.:.:..|.::|||..||:::...: ..:.|..:||.:..:||     .:|.:..
  Fly   231 ----EKIKHLVALYQGSDTRVILDLTPNYAAKNSQ-LVQDAIANPEKRSAFVW-----VSGGKAL 285

  Fly   179 PSNWISVFRGSAWQWHEGRQEFYLHQFVKKQPDLNYRNPKVRETMSNVLRFWLGKGVAGFRIDAV 243
            |:||:.| .|:...|.:....:.|.||.....||...:..:|.....||:..:..||.|||:...
  Fly   286 PNNWLKV-GGNRSAWEKVGDNYVLSQFEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNT 349

  Fly   244 PH--VFEIAPDNQNQYRDEPRNDWDNDPEDYGYLQHIYTKDQPETIDLVYSWRAVLDAHQREHGG 306
            ..  :|:...|  .|....|: |:...|.:||:..|..|.......|::|.:.:::    :....
  Fly   350 KFFALFDSLED--EQISSSPK-DFSLGPNEYGFYSHRQTTFLSGLGDVLYDYLSIV----KNASD 407

  Fly   307 EDRILMAETYSPIDI----VMQYYGNATAEGAQLPFNFLLISELSNS----------SNAHAYEG 357
            |....:||     |:    |.|..|::.|.|..||.....:..||.|          .|..|..|
  Fly   408 EAFFSVAE-----DVMEPQVYQLSGDSGAYGIDLPMYGNFVKVLSKSKPDTSLQKELDNTLAQSG 467

  Fly   358 TVLKWLQHMPKGRTANWVLGN--HDQPRVGSRLGRDRVDMLNMLTATLPGASVTYQGEELGMTNV 420
            |. .|||         |.|.:  .|.|:..|.|.        |..:.|||..|.
  Fly   468 TD-SWLQ---------WNLADVYVDTPQDPSALA--------MFLSLLPGVPVV----------- 503

  Fly   421 WISWKDTVDPSACNTNPSIYEQYSRDPERTPFQWTDAQDAGFSNASKTWLPIAVDYKEVNVEQER 485
                  .||                                           ||.|:.|..|
  Fly   504 ------AVD-------------------------------------------AVAYQNVTEE--- 516

  Fly   486 QKPLSHLNVFKQLWQLRKQSQTLKRGETEVKALSDAVLAVKRYLERDSTYLTLLNIYDGVETINL 550
                    .::|:..|||.:..:.......:|  |.::|..|....:..|..:.|..:..:..|.
  Fly   517 --------TYRQITSLRKTASYMHGNLNLYQA--DPLVAFSRIKSGNPGYFVIFNPTELPQASNF 571

  Fly   551 LQSFPD-LPPQLKVVVVTER--------SQVKVGDLVNSTSLQLQPKDSLVL 593
              :.|| ||.::.|...:|:        .:|.....||...|::.|..|::|
  Fly   572 --TIPDNLPDKMTVSYFSEQYNNNMDNSGKVAHAGRVNLKDLKVAPHSSIIL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A5	NP_610382.2	AmyAc_maltase	41..514	CDD:200467	99/490 (20%)
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	125/607 (21%)