Protein Alignment Mal-A4 and IMA1

DIOPT Version :10

• Sequence 1: NP_610381.1
• Gene: Mal-A4 / 35827
• FlyBaseID: FBgn0033294
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_011803.3
• Gene: IMA1 / 853204
• SGDID: S000003519
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 635
• Identity: 201/635 - (31%)
• Similarity: 296/635 - (46%)
• Gaps: 134/635 - (21%)

  Fly    16 LAVDAAAP-----WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTATWLSPFLKS 75
            :.:.:|.|     |||.|:||||||.|||||:.:|.||:.|:..||||:||:|..|.|:|||..|
Yeast     1 MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDS 65

  Fly    76 PMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLRSAAGEEEY 140
            |..|.||||::::.|.|.:||.||...::.:..:||:|.|.|.|.||.|.|.:||..|.:.:...
Yeast    66 PQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNP 130

  Fly   141 K-DYYMWHP--GFLDEDGTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDFNFRNPVVRE 202
            | |::.|.|  |: |.:|...||.||.|.|.||||.:.|..||:||..|...|||.|:.|...|:
Yeast   131 KRDWFFWRPPKGY-DAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRK 194

  Fly   203 EM-NNVLRFWLEKGVDGFRVD--AIYHAFEIEADENGNYPDEP----RNDW-TNDPDEYGYTHKI 259
            .: .:.:.:||:.||||||:|  ::|       .:....||.|    .:.| ::||
Yeast   195 AIYESAVGYWLDHGVDGFRIDVGSLY-------SKVVGLPDAPVVDKNSTWQSSDP--------- 243

  Fly   260 YTVDQPETPHLVYEWRQILEQFQADNGGDERILMV--ETWSPIEIVMHYYGNETADGAQIPFNFQ 322
            ||::.|.    ::|:.|.:.||..:...|.|.:|.  |.....:.....|.:.:.......|||.
Yeast   244 YTLNGPR----IHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSELFNFS 304

  Fly   323 LISNLHYD---SDAYHYE---YLINNWLNLMPE------GKSANW---VIGNHDKNRVGSRFGAD 372
                 |.|   |..:.|.   :.:.:|...:.|      |... |   .:.|||:.|..:|||.|
Yeast   305 -----HTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDC-WSTIYLENHDQPRSITRFGDD 363

  Fly   373 ----RV---DLFNILLLTLPGCSITYQGEELGMLDGYVSW--EDTVDPQACNGYEA---NYMDN- 424
                ||   .|.::||..|.|....|||:|||.:: :.:|  |...|.:..|.|.|   .:.:|
Yeast   364 SPKNRVISGKLLSVLLSALTGTLYVYQGQELGQIN-FKNWPVEKYEDVEIRNNYNAIKEEHGENS 427

  Fly   425 -------------SRDPARTPMHWS-DETMAGFTTGNST--WLPVSTDYRQR-NVKTERGVSLSH 472
                         |||.|||||.|| :|..||| :|.|.  |..::..:|:. ||:.|.....|.
Yeast   428 EEMKKFLEAIALISRDHARTPMQWSREEPNAGF-SGPSAKPWFYLNDSFREGINVEDEIKDPNSV 491

  Fly   473 LNVFKRLQQLRQEPSIEEGSAEVKAVSNYVLAVKRHLSGDFVYISLFN--IFDSIENVNLSSVFG 535
            ||.:|...:.|:..         |.::.|        ..||.:|.|.|  :|...:..|..::|.
Yeast   492 LNFWKEALKFRKAH---------KDITVY--------GYDFEFIDLDNKKLFSFTKKYNNKTLFA 539

  Fly   536 SL----------------PAKFQYALVTEKSIKKVGDQVSAGSVTLMPHE 569
            :|                ..|.::....:|       :|.|.|.||.|.|
Yeast   540 ALNFSSDATDFKIPNDDSSFKLEFGNYPKK-------EVDASSRTLKPWE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A4	NP_610381.1	AmyAc_maltase	24..492	CDD:200467	179/525 (34%)
IMA1	NP_011803.3	AmyAc_SI_OligoGlu_DGase	16..503	CDD:200472	176/515 (34%)
		Malt_amylase_C	514..585	CDD:445893	18/76 (24%)