Protein Alignment Mal-A4 and MAL32

DIOPT Version :10

• Sequence 1: NP_610381.1
• Gene: Mal-A4 / 35827
• FlyBaseID: FBgn0033294
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_009858.3
• Gene: MAL32 / 852602
• SGDID: S000000503
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 614
• Identity: 192/614 - (31%)
• Similarity: 282/614 - (45%)
• Gaps: 117/614 - (19%)

  Fly    24 WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTATWLSPFLKSPMADFGYDISDFK 88
            |||.|:.|||||.|||||:.:|.|||.|:|.||:|:|::||.|.|:.||..||..|.|||||:::
Yeast    13 WWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYE 77

  Fly    89 AVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLRSAAGEEEYK-DYYMWHP--GF 150
            .|.|.:||.||...::.:..:||:|.|.|.|.||.|.|.:||..|.:.:...| |::.|.|  |:
Yeast    78 KVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGY 142

  Fly   151 LDEDGTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDFNFRNPVVREEM-NNVLRFWLEK 214
             |.:|...||.||.|.|.||||.:.|...|:||..|..:|.|.|:.|...|..: .:.:.|||:.
Yeast   143 -DAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDH 206

  Fly   215 GVDGFRVD--AIYHAFEIEADENGNYPDEPRNDWTNDPDEYGY-THKIYTVDQPETPHLVYEWRQ 276
            ||||||:|  .:|       .:....||.|..|.|:......: :|     :.|.    ::|:.|
Yeast   207 GVDGFRIDTAGLY-------SKRPGLPDSPIFDKTSKLQHPNWGSH-----NGPR----IHEYHQ 255

  Fly   277 ILEQFQADNGGDERILMVETWSPIEIVMHYYGNETA---DGAQIPFNFQLISNLHYD---SDAYH 335
            .|.:|..:...|.|.:|.     :..|.|  |::.|   ..|:...: ::.|..|.:   |..:.
Yeast   256 ELHRFMKNRVKDGREIMT-----VGEVAH--GSDNALYTSAARYEVS-EVFSFTHVELGTSPFFR 312

  Fly   336 Y-----------EYLINNWLNLMPEGKSANWVIGNHDKNRVGSRFGADRVDLFNI--LLLTLPGC 387
            |           |.:.:|:|.:......|...|.|||:.|..:||..|......|  .||||..|
Yeast   313 YNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLEC 377

  Fly   388 SIT-----YQGEELGMLDGYVSW--EDTVDPQACNGYE---ANYMDN--------------SRDP 428
            |:|     |||:|:|.:: :..|  |...|....|.||   .::..|              |||.
Yeast   378 SLTGTLYVYQGQEIGQIN-FKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDH 441

  Fly   429 ARTPMHWS-DETMAGFTTGN-STWLPVSTDYRQR-NVKTERGVSLSHLNVFKRLQQLRQE----- 485
            :||||.|: |:..||||..: ..|..::..:.|. ||:.|.....|.||.:||..|.|::
Yeast   442 SRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELM 506

  Fly   486 ------PSIEEGSAEV----KAVSNYVLAVKRHLSGDFVYISLFNIFDSIENVNLSSVFGSLPAK 540
                  ..|:..|.::    |...:..|....:.||:.:..||     ..|..:||.:.|:.
Yeast   507 IYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSL-----PREGASLSFILGNY--- 563

  Fly   541 FQYALVTEKSIKKVGDQVSAGSVTLMPHE 569
                           |.....|..|.|.|
Yeast   564 ---------------DDTDVSSRVLKPWE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A4	NP_610381.1	AmyAc_maltase	24..492	CDD:200467	176/531 (33%)
MAL32	NP_009858.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	173/511 (34%)
		Malt_amylase_C	511..583	CDD:435493	17/90 (19%)