Protein Alignment Mal-A4 and slc3a1

DIOPT Version :10

• Sequence 1: NP_610381.1
• Gene: Mal-A4 / 35827
• FlyBaseID: FBgn0033294
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_021336428.1
• Gene: slc3a1 / 557757
• ZFINID: ZDB-GENE-090313-225
• Length: 674
• Species: Danio rerio
• Alignment Length: 587
• Identity: 230/587 - (39%)
• Similarity: 339/587 - (57%)
• Gaps: 66/587 - (11%)

  Fly     4 WTSLFLLLGLGLLAVDAA----AP----WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLK 60
            |  |.:...|.|:|:.||    :|    ||:.:..||:||||||||:.:|||||.|:.|||.:.:
Zfish    81 W--LVIACTLALIAMTAAIVALSPRCMSWWQLSPIYQVYPRSFKDSNADGVGDLRGIKEKLSHFE 143

  Fly    61 EIGVTATWLSPFLKSPMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSD 125
            .:.:.|.|:|||.||||.|||||:.||:.|||||||||||:::::...:.|:|:|:|::|||:||
Zfish   144 YLNIKAIWISPFYKSPMRDFGYDVEDFRDVDPLFGTMEDFDDLLTSMHDKGLKLIMDYIPNHTSD 208

  Fly   126 ECDWFLRSAAGEEEYKDYYMWHPGFLDEDGTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQ 190
            :..||..|....|.|.|||:|.....|     :.|.||||||..|.||:.|.||:.|.|||.|:|
Zfish   209 KHVWFQLSRNYTEPYTDYYIWVNCTAD-----KHPNNWVSVFGNSTWEYDEIRQQCYFHQFLKEQ 268

  Fly   191 PDFNFRNPVVREEMNNVLRFWLEKGVDGFRVDAIYHAFEIEADENGNYPDEPRNDWTNDPD---- 251
            ||.|:|||:|.:||.:::.|||:|||||||:||:.|..|..     :..|||:.:...||.
Zfish   269 PDLNYRNPLVLQEMTDIIHFWLKKGVDGFRMDAVKHMLEAT-----HLRDEPQVNPDQDPSTVDT 328

  Fly   252 EYGYTHKIYTVDQPETPHLVYEWRQILEQFQADNGGDERILMVETWSPIEI--VMHYYGNETADG 314
            |:...|. ||..|.....::.:||..::.:..: .|..|.:::|::...||  .|.|||...|..
Zfish   329 EFELYHD-YTYTQAGLHEILTDWRIQMDTYSRE-PGRYRFMVMESYDYEEIDKTMRYYGTNYAKE 391

  Fly   315 AQIPFNFQLISNLHYDSDAYHYEYLINNWLNLMPEGKSANWVIGNHDKNRVGSRFGADRVDLFNI 379
            :..||||.|: :|..:....:.:.::..|::.||:||..|||:|||||.|:||..|.:.|...|:
Zfish   392 SDFPFNFYLL-DLPDNLSGNYAKSIVERWMSNMPKGKWPNWVVGNHDKPRIGSSAGKEYVRALNM 455

  Fly   380 LLLTLPGCSITYQGEELGMLDGYVSWEDTVDPQACNGYEANYMDNSRDPARTPMHWSDETMAGFT 444
            |||||||...||.|||:||:|..:|    |.......|:.:   .||||.||||.|::|..|||:
Zfish   456 LLLTLPGTPTTYYGEEIGMVDVNIS----VIQDPAGQYDPS---KSRDPQRTPMQWNNELNAGFS 513

  Fly   445 TG-NSTWLPVSTDYRQRNVKTERGVSLSHLNVFKRLQQLRQEPSIEEGSAEVKAVSNYVLAVKRH 508
            .. |.|||.:::|||..||:.::..:.|.::.::.|..||.              ||.:|:
Zfish   514 ESLNGTWLDIASDYRTVNVEVQQDDTSSTISQYRALSLLRS--------------SNVILS---- 560

  Fly   509 LSGDFVYI-SLFNIFDSIENVN-LSSVFGSLPAKFQYALVTE-KSIKKVGDQVSAGSVTL-MPHE 569
             .|.|.|: :..|:|..:..:: ||..| .:...|.....|: .|:|::.|     |:|| :..|
Zfish   561 -RGWFCYVWNDVNVFAYLRELDGLSKGF-LVVLNFGKETTTDLSSVKELPD-----SLTLHLSTE 618

  Fly   570 SI 571
            ||
Zfish   619 SI 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A4	NP_610381.1	AmyAc_maltase	24..492	CDD:200467	200/474 (42%)
slc3a1	XP_021336428.1	SLC3A2_N	55..114	CDD:464983	10/34 (29%)
		AmyAc_SLC3A1	106..563	CDD:200494	203/495 (41%)