Protein Alignment Mal-A4 and Slc3a1

DIOPT Version :10

• Sequence 1: NP_610381.1
• Gene: Mal-A4 / 35827
• FlyBaseID: FBgn0033294
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_033231.2
• Gene: Slc3a1 / 20532
• MGIID: 1195264
• Length: 685
• Species: Mus musculus
• Alignment Length: 589
• Identity: 216/589 - (36%)
• Similarity: 323/589 - (54%)
• Gaps: 38/589 - (6%)

  Fly     3 TWTSLFLLLGLGLLAVDAAAP----WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIG 63
            |..|:|||:| ..:|:...:|    ||:....||||||||||||.:|.|||.|:.|||:|:..:.
Mouse    92 TVVSVFLLIG-ATIAIIVISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALN 155

  Fly    64 VTATWLSPFLKSPMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECD 128
            :...|::.|.||.:.||.|.:.|||.:||:||||:||||:|:...:.|:|:|:||:|||:||:..
Mouse   156 IKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHP 220

  Fly   129 WFLRSAAGEEEYKDYYMWHPGFLDEDGTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDF 193
            ||..|.....:|.|||:|| .....:|...||.||:||:..|:|.:.|.|::.|.|||.|:|||.
Mouse   221 WFQSSRTRSGKYTDYYIWH-NCTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDL 284

  Fly   194 NFRNPVVREEMNNVLRFWLEKGVDGFRVDAIYHAFEIEADENGNYPDEPRNDWTNDPD---EYGY 255
            |||||.|:||:..::.|||.||||||..||:  .|.:||.:..|   |.:.:.:..||   .|..
Mouse   285 NFRNPAVQEEIKEIITFWLSKGVDGFSFDAV--KFLLEAKDLRN---EIQVNTSQIPDTVTHYSE 344

  Fly   256 THKIYTVDQPETPHLVYEWRQILEQFQADNGGDERILMVETWSPIEIVMHYYGNETADGAQIPFN 320
            .:..:|..|.....:|.::||.:.|:..:.|....:....:...||..|.|||......|..|||
Mouse   345 LYHDFTTTQVGMHDIVRDFRQTMNQYSREPGRYRFMGAEASAESIERTMMYYGLPFIQEADFPFN 409

  Fly   321 --FQLISNLHYDSDAYHYEY-LINNWLNLMPEGKSANWVIGNHDKNRVGSRFGADRVDLFNILLL 382
              |..|..|     :.|..| :|.:|:..|||||..||:.|..:..|:.||.|::.|:..::||.
Mouse   410 KYFTTIGTL-----SGHTVYEVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVNAMHMLLF 469

  Fly   383 TLPGCSITYQGEELGMLDGYVSWEDTVDPQACNGYEANYMDNSRDPARTPMHWSDETMAGFTTGN 447
            ||||..|||.|||:||.|..|:           .:..:| |::...:::||.|.:.:.||||..|
Mouse   470 TLPGTPITYYGEEIGMGDISVT-----------NFNESY-DSTTLVSKSPMQWDNSSNAGFTEAN 522

  Fly   448 STWLPVSTDYRQRNVKTERGVSLSHLNVFKRLQQLR-QEPSIEEGSAEVKAVSNYVLAVKRHLSG 511
            .||||.::||...||..::....|.|.:::.|..|. .|..:..|...:....::.:...|.|.|
Mouse   523 HTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLSRGWFCLLRDDSHSVVYTRELDG 587

  Fly   512 -DFVYISLFNIFDSIENVNLSSVFGSLPAKFQYALVTEKSIKKVGDQVSAGSVTLMPHESIVLRS 575
             |.|::.:.|..:|...:||..:...||.:.:..|.|..:.|  |..|...:::|...|.:||..
Mouse   588 IDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASK--GSAVDTRAISLEKGEGLVLEH 650

  Fly   576 TTTA 579
            :|.|
Mouse   651 STKA 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A4	NP_610381.1	AmyAc_maltase	24..492	CDD:200467	185/474 (39%)
Slc3a1	NP_033231.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		SLC3A2_N	64..123	CDD:464983	10/31 (32%)
		AmyAc_SLC3A1	115..568	CDD:200494	185/475 (39%)