Protein Alignment Mal-A2 and MAL12

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_011808.3
• Gene: MAL12 / 853209
• SGDID: S000003524
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 607
• Identity: 182/607 - (29%)
• Similarity: 274/607 - (45%)
• Gaps: 116/607 - (19%)

  Fly    27 WWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNFY 91
            ||:.|::|||||.||:||:.||.||||||||:|.|:|::|:.|.|:.|.:.||..|.||||||:.
Yeast    13 WWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYE 77

  Fly    92 DIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKS-VNREDGYDDFYVWDDGKLN 155
            .:.|.:||.||..:||.:...||:|.|.|.|.||.|.|:.||::| .::.:...|::.|...|..
Yeast    78 KVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGY 142

  Fly   156 EETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLD-VLKFWLDRG 219
            :..|...||:||.|.|.|..||::|...:::|..|..:|.|||:.|...|..:.: .:.||||.|
Yeast   143 DAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHG 207

  Fly   220 VDGFRIDAVPHIYEHRNADGSYPDEPV---------SGWGS--DPNAYDYHD--HIYTKDQPATV 271
            |||||||.. .:|..|   ...||.|:         ..|||  .|..::||.  |.:.|::
Yeast   208 VDGFRIDTA-GLYSKR---PGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNR---- 264

  Fly   272 DLMYEWREFLDNYRAQNGGDSRVLLAEAYSSVETLSAYFGNSTH--QGTQLPMNFQLMYLSGYST 334
              :.:.||.:......:|.|:.:..:.|...|..:.::    ||  .||.....:.::..    |
Yeast   265 --VKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF----THVEVGTSPFFRYNIVPF----T 319

  Fly   335 AKDVVGSIDYWMNTMWKE---------HQTANWV---VGNHDTNRVADRMG-----AHKVD--LL 380
            .|            .|||         :.|.:|.   :.|||..|...|..     ..|:.  ||
Yeast   320 LK------------QWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLL 372

  Fly   381 NVIVNALPGASVTYYGEEIGMSN-----------VDVE--------------------CTGDSCE 414
            .::..:|.|....|.|:|||..|           |||:                    ..|.:..
Yeast   373 TLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALL 437

  Fly   415 DRDGERTPMQWTAGK-NADFSDGE-STWLPLSPEY-QRYNVQTERGVSRSSLNIFK-GLQELKSS 475
            .||..||||.||..| ||.|:..: ..|..|:..: |..||:.|.....|.||.:| .||..|..
Yeast   438 SRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKY 502

  Fly   476 SAFLAFKEDGGFSYEAVTEQVLQIIRTNKISEEYRILVNMGNGMEILDGLAPK---TYEYVLATA 537
            ...:.:    |:.::.:.....||....|..|:..:...:....|.::...|:   :..::|...
Yeast   503 KELMIY----GYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY 563

  Fly   538 YSTHYSGQKADLSQRIILMPYE 559
            ..|       |:|.| :|.|:|
Yeast   564 DDT-------DVSSR-VLKPWE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	167/527 (32%)
MAL12	NP_011808.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	164/515 (32%)
		Malt_amylase_C	511..583	CDD:435493	14/75 (19%)