Protein Alignment Mal-A2 and IMA1

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_011803.3
• Gene: IMA1 / 853204
• SGDID: S000003519
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 535
• Identity: 179/535 - (33%)
• Similarity: 260/535 - (48%)
• Gaps: 99/535 - (18%)

  Fly    27 WWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNFY 91
            ||:.|:.|||||.||:||:.||.||:|||.|:|.|:||:|..|.|:||.:.||..|.||||:|:.
Yeast    14 WWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYE 78

  Fly    92 DIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKS-VNREDGYDDFYVWDDGKLN 155
            .:.|.:||.||...||.:...||:|.|.|.|.||.|.|:.||::| .::.:...|::.|...|..
Yeast    79 KVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGY 143

  Fly   156 EETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLD-VLKFWLDRG 219
            :..|...||:||.|.|.|..||::||.|:::|..|...|||||:.|...|:.:.: .:.:|||.|
Yeast   144 DAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHG 208

  Fly   220 VDGFRIDAVPHIYEHRNADGSYPDEPV----SGW-GSDPNAYDYHDHIYTKDQPATVDLMYEWRE 279
            ||||||| |..:|   :.....||.||    |.| .|||         ||.:.|...:...|..:
Yeast   209 VDGFRID-VGSLY---SKVVGLPDAPVVDKNSTWQSSDP---------YTLNGPRIHEFHQEMNQ 260

  Fly   280 FLDNYRAQNGGDSRVLLAEAYSSVETLSAYFGNSTHQGTQLPMNFQ-----LMYLSGYSTA---- 335
            |:.| |.::|.:...:....::|.||...|...|.|:.::| .||.     ...|..|:..
Yeast   261 FIRN-RVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL-FNFSHTDVGTSPLFRYNLVPFEL 323

  Fly   336 KD----------VVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMG----AHKV---DLLNVI 383
            ||          .:...|.| :|::.|         |||..|...|.|    .::|   .||:|:
Yeast   324 KDWKIALAELFRYINGTDCW-STIYLE---------NHDQPRSITRFGDDSPKNRVISGKLLSVL 378

  Fly   384 VNALPGASVTYYGEEIGMSNV---------DVECT----------GDSCED------------RD 417
            ::||.|....|.|:|:|..|.         |||..          |::.|:            ||
Yeast   379 LSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALISRD 443

  Fly   418 GERTPMQWTAGK-NADFSDGEST--WLPLSPEYQR-YNVQTERGVSRSSLNIFK-GLQELKSSSA 477
            ..||||||:..: ||.|| |.|.  |..|:..::. .||:.|.....|.||.:| .|:..|:...
Yeast   444 HARTPMQWSREEPNAGFS-GPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRKAHKD 507

  Fly   478 FLAFKEDGGFSYEAV 492
            ...:    |:.:|.:
Yeast   508 ITVY----GYDFEFI 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	177/525 (34%)
IMA1	NP_011803.3	AmyAc_SI_OligoGlu_DGase	16..503	CDD:200472	174/512 (34%)
		Malt_amylase_C	514..585	CDD:445893	1/5 (20%)