Protein Alignment Mal-A2 and slc3a1

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_021336428.1
• Gene: slc3a1 / 557757
• ZFINID: ZDB-GENE-090313-225
• Length: 674
• Species: Danio rerio
• Alignment Length: 511
• Identity: 197/511 - (38%)
• Similarity: 305/511 - (59%)
• Gaps: 40/511 - (7%)

  Fly    25 IDWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISN 89
            :.||:.:.:||:|||||:||:.||:|||:||..:|.:.:.:.|.|.|:||.:.|||.|||||:.:
Zfish   105 MSWWQLSPIYQVYPRSFKDSNADGVGDLRGIKEKLSHFEYLNIKAIWISPFYKSPMRDFGYDVED 169

  Fly    90 FYDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVNREDGYDDFYVWDDGKL 154
            |.|:||:|||:||||||:......|:|:|:|::|||:||::|||:.|.|..:.|.|:|:|.:...
Zfish   170 FRDVDPLFGTMEDFDDLLTSMHDKGLKLIMDYIPNHTSDKHVWFQLSRNYTEPYTDYYIWVNCTA 234

  Fly   155 NEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLDVLKFWLDRG 219
            ::.      |:||||||....|.::|.|||.:.|||..:|||||:.||:|.:.|.|::.|||.:|
Zfish   235 DKH------PNNWVSVFGNSTWEYDEIRQQCYFHQFLKEQPDLNYRNPLVLQEMTDIIHFWLKKG 293

  Fly   220 VDGFRIDAVPHIYEHRNADGSYPDEPVSGWGSDPNAYD-----YHDHIYTKDQPATVDLMYEWRE 279
            |||||:|||.|:.|..:    ..|||......||:..|     |||:.||  |....:::.:||.
Zfish   294 VDGFRMDAVKHMLEATH----LRDEPQVNPDQDPSTVDTEFELYHDYTYT--QAGLHEILTDWRI 352

  Fly   280 FLDNYRAQNGGDSRVLLAEA--YSSVETLSAYFGNSTHQGTQLPMNFQLM----YLSGYSTAKDV 338
            .:|.| ::..|..|.::.|:  |..::....|:|.:..:.:..|.||.|:    .||| :.||.:
Zfish   353 QMDTY-SREPGRYRFMVMESYDYEEIDKTMRYYGTNYAKESDFPFNFYLLDLPDNLSG-NYAKSI 415

  Fly   339 VGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGAHKVDLLNVIVNALPGASVTYYGEEIGMSN 403
            |   :.||:.|.| .:..||||||||..|:....|...|..||:::..|||...|||||||||.:
Zfish   416 V---ERWMSNMPK-GKWPNWVVGNHDKPRIGSSAGKEYVRALNMLLLTLPGTPTTYYGEEIGMVD 476

  Fly   404 VDVECTGDSC------EDRDGERTPMQWTAGKNADFSDG-ESTWLPLSPEYQRYNVQTERGVSRS 461
            |::....|..      :.||.:||||||....||.||:. ..|||.::.:|:..||:.::..:.|
Zfish   477 VNISVIQDPAGQYDPSKSRDPQRTPMQWNNELNAGFSESLNGTWLDIASDYRTVNVEVQQDDTSS 541

  Fly   462 SLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIR-TNKISEEYRILVNMG 516
            :::.::.|..|:||:..|:   .|.|.|......|...:| .:.:|:.:.:::|.|
Zfish   542 TISQYRALSLLRSSNVILS---RGWFCYVWNDVNVFAYLRELDGLSKGFLVVLNFG 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	189/476 (40%)
slc3a1	XP_021336428.1	SLC3A2_N	55..114	CDD:464983	2/8 (25%)
		AmyAc_SLC3A1	106..563	CDD:200494	189/477 (40%)