Protein Alignment Mal-A2 and AMY1B

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001008219.1
• Gene: AMY1B / 277
• HGNCID: 475
• Length: 511
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 86/441 - (19%)
• Similarity: 139/441 - (31%)
• Gaps: 178/441 - (40%)

  Fly    98 GTLEDFDDLIVEAKSLGVKIILDFVPNH----------SSDENVWFEKSVNREDGYDDFYV---- 148
            |..::|.:::....::||:|.:|.|.||          ||....:|      ..|..||..
Human    89 GNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYF------NPGSRDFPAVPYS 147

  Fly   149 -WD--DGKLNEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQ------PDLNFTNPMV 204
             ||  |||.  :||            ||.:..:|:..        ||:.      .||......|
Human   148 GWDFNDGKC--KTG------------SGDIENYNDAT--------QVRDCRLSGLLDLALGKDYV 190

  Fly   205 REHMLDVLKFWLDRGVDGFRIDAVPHIYE----------HRNADGSYPD-------EPVSGWGSD 252
            |..:.:.:...:|.||.||||||..|::.          |......:|:       :.|...|.:
Human   191 RSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNWFPEGSKPFIYQEVIDLGGE 255

  Fly   253 P-NAYDYHDH--------------IYTKDQPATVDLMYEWRE------------FLDNYRAQNG- 289
            | .:.||..:              :..|.....:..:..|.|            |:||:..|.|
Human   256 PIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGH 320

  Fly   290 ----------GDSRV-------LLAEAYSSVETLSAYFGNSTHQGTQLPMNFQLMYLSGYSTAKD 337
                      .|:|:       :||..|.....:|:|         :.|..|:        ..||
Human   321 GAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSY---------RWPRYFE--------NGKD 368

  Fly   338 V---VG-------------------SIDYWMNTMWKEHQT-------------ANWVVGNHDTNR 367
            |   ||                   ..|:.....|::.:.             .||.  ::.:|:
Human   369 VNDWVGPPNDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWY--DNGSNQ 431

  Fly   368 VADRMGAHKVDLLN--------VIVNALPGASVTYYGEEIGMSNVDVECTG 410
            ||...|.....:.|        .:...||..:   |.:.|....::..|||
Human   432 VAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGT---YCDVISGDKINGNCTG 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	86/441 (20%)
AMY1B	NP_001008219.1	AmyAc_bac_euk_AmyA	25..416	CDD:200456	72/371 (19%)
		Aamy_C	422..510	CDD:214749	14/63 (22%)