Protein Alignment Mal-A2 and mal1

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_595063.1
• Gene: mal1 / 2539976
• PomBaseID: SPBC1683.07
• Length: 579
• Species: Schizosaccharomyces pombe
• Alignment Length: 602
• Identity: 176/602 - (29%)
• Similarity: 289/602 - (48%)
• Gaps: 98/602 - (16%)

  Fly    26 DWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNF 90
            :||...|:|||||.||:||:|||.|||:||.|::.|||.:.:.:.||.||:.||:.|.|||:|::
pombe    12 NWWRETSVYQIYPASFKDSNGDGFGDLEGIISKVDYLKALNVESIWLCPIYPSPLKDMGYDVSDY 76

  Fly    91 YDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKS-VNREDGYDDFYVWDDGKL 154
            ..||..:|||||.|.|:.......:|:::|.|.||:||::.||::| .::.:...|:|.|...:.
pombe    77 KQIDSRYGTLEDLDRLMKALHERDMKLVMDLVLNHTSDQHEWFKESRSSKTNPKRDWYFWKPARY 141

  Fly   155 NEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLDVLKFWLDRG 219
            ||: |.|.||:||.|.|....|.|:|..|:|:||.:.|.|||||:..|.|||.:.|:|:||||||
pombe   142 NEK-GERLPPNNWRSYFDTSAWEWDEATQEYYLHLWSVGQPDLNWETPKVREAVHDILRFWLDRG 205

  Fly   220 VDGFRIDAVPHIYEHRNADGSYPDEPVSGWGSDPNAYDYH-DHIYTKDQPATVDLMYEWREFLDN 283
            |||||:||:..|    :.|..:.|.|::     .:.|:|. .:.|..:.|...:.:......|..
pombe   206 VDGFRLDAINMI----SKDQRFLDAPIT-----DDRYEYQLAYQYYANGPRIHEYLNGIGNILTE 261

  Fly   284 YRAQNGGDSRVLLAEAYSSVETLSAYFGNSTHQGTQLPMNFQL------------MYLSGYSTAK 336
            |.|.:.|:...:| :....:..:.|       ...:|.|.||.            .|:.|.....
pombe   262 YDAFSVGEMPYVL-DTNEILHVVGA-------DRRELTMIFQFDFVDLDLDPNQHKYIEGSWELS 318

  Fly   337 DVVGSIDYWMNTMWKEHQTANW---VVGNHDTNRVADR-------MGAHKVDLLNVIVNALPGAS 391
            |:..|:..|.:.:.   ....|   .:.|||..|...|       ..|:...|:.:.:....|..
pombe   319 DLKKSLKKWQSALL---SGGGWNASFIENHDQTRTVSRYLSDSPKYRAYSSKLMALFIIFQSGTP 380

  Fly   392 VTYYGEEIGMSNV----------DVE--------CTGDSCED-------------RDGERTPMQW 425
            ..:.|:|:.::|:          |||        .:|:..::             ||..||||.|
pombe   381 FVFQGQELALANIPRDWPIDEYLDVETQNFWKLFMSGNPSQEEIEKTMDIVNKRARDNGRTPMHW 445

  Fly   426 TAGKNADFSD-GESTWLPLSPEYQRYNVQTERGVSRSSLNIF-KGLQ---ELKSSSAFLAFKEDG 485
            .:..|..|:. |...|:.::.:|:.:|...:.....|....: |.|:   |||.:..:
pombe   446 DSSPNGGFTKAGVKPWMRVTNDYKEWNAANQVNDPESPYTFWSKALELRKELKDAVVY------- 503

  Fly   486 GFSYEAVTEQVLQIIRTNKISEEYRILVNM---GNGMEILDGLAPKTYEYVLATAYSTHYSGQKA 547
             .|:|.::|:...|:...:.|..|::::.:   ||.:.....|...:|| :|...|.....
pombe   504 -GSFELISEEDPSIVAFVRESSTYKLIILLNFTGNKVSYDCPLNLTSYE-ILLDNYKDFIC---- 562

  Fly   548 DLSQRIILMPYEAVVLR 564
             ::..:.|.||:||:|:
pombe   563 -MTSPVTLNPYQAVLLK 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	157/517 (30%)
mal1	NP_595063.1	AmyAc_SI_OligoGlu_DGase	15..496	CDD:200472	152/501 (30%)
		Malt_amylase_C	504..>544	CDD:445893	8/39 (21%)