Protein Alignment Mal-A2 and Slc3a2

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001154885.1
• Gene: Slc3a2 / 17254
• MGIID: 96955
• Length: 565
• Species: Mus musculus
• Alignment Length: 576
• Identity: 114/576 - (19%)
• Similarity: 191/576 - (33%)
• Gaps: 201/576 - (34%)

  Fly    27 WWENASLYQIYP-RSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNF 90
            ||...:||:|.. ::|...|..||..||   |.|.||..:.:....|.||..:...:.  :.::.
Mouse   150 WWHKGALYRIGDLQAFVGRDAGGIAGLK---SHLEYLSTLKVKGLVLGPIHKNQKDEI--NETDL 209

  Fly    91 YDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVNREDGYDDFYVWDDGKLN 155
            ..|:|..|:.|||.||:..||...:.||||..||:.. :|.||..:
Mouse   210 KQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNYQG-QNAWFLPA------------------- 254

  Fly   156 EETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLDVLKFWLDRGV 220
                                                  |.|:      |...|.:.|..||..||
Mouse   255 --------------------------------------QADI------VATKMKEALSSWLQDGV 275

  Fly   221 DGFRIDAVPHIYEHRNADGSYPDEPVSGWGSDPNAYDYHDHIYTKDQPATVDLMYEWREFLDNYR 285
            |||:...|          |...:.|:                          .:.||:..
Mouse   276 DGFQFRDV----------GKLMNAPL--------------------------YLAEWQNI----- 299

  Fly   286 AQNGGDSRVLLA--------------EAYSSVETLSAYFGNSTHQGTQLPMNFQLMYLSGYSTAK 336
            .:|..:.|:|:|              |:.|.:...|:|..|||..|.:..        |..:...
Mouse   300 TKNLSEDRLLIAGTESSDLQQIVNILESTSDLLLTSSYLSNSTFTGERTE--------SLVTRFL 356

  Fly   337 DVVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGAHKVDLLNVIVNALPGASVTYYGEEIGM 401
            :..||            |..:|.|.  ....:||.:..|.:.|..:::..|||..|..||:|:|:
Mouse   357 NATGS------------QWCSWSVS--QAGLLADFIPDHLLRLYQLLLFTLPGTPVFSYGDELGL 407

  Fly   402 SNVDVECTGDSCEDRDGERTPMQWTAGKNADFSDGESTWLPLSP--EYQRYNV-------QTERG 457
            ...                             ..|:....||.|  |...:::       .|.:|
Mouse   408 QGA-----------------------------LPGQPAKAPLMPWNESSIFHIPRPVSLNMTVKG 443

  Fly   458 VSR---SSLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIRTNKISEEYRILVNMGN-- 517
            .:.   |.|..|:.|.:|:.....|.   .|.|...:.:..:...||....:|.|.:::|..:
Mouse   444 QNEDPGSLLTQFRRLSDLRGKERSLL---HGDFHALSSSPDLFSYIRHWDQNERYLVVLNFRDSG 505

  Fly   518 ------GMEILDGLA-PKTYEYVLATAYSTHYSGQKADLS-QRIILMPYEAVVLRW 565
                  ...:..|:: |.:.:.:|:|..:.....:...|. :.:.|.|||.::|::
Mouse   506 RSARLGASNLPAGISLPASAKLLLSTDSARQSREEDTSLKLENLSLNPYEGLLLQF 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	97/483 (20%)
Slc3a2	NP_001154885.1	SLC3A2_N	84..157	CDD:464983	2/6 (33%)
		AmyAc_family	139..468	CDD:476817	96/478 (20%)