Protein Alignment Mal-A2 and LOC1280462

DIOPT Version :10

• Sequence 1: NP_476625.2
• Gene: Mal-A2 / 35825
• FlyBaseID: FBgn0002569
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_320158.1
• Gene: LOC1280462 / 1280462
• VectorBaseID: AGAMI1_002996
• Length: 599
• Species: Anopheles gambiae
• Alignment Length: 579
• Identity: 281/579 - (48%)
• Similarity: 375/579 - (64%)
• Gaps: 39/579 - (6%)

  Fly     9 LAALLLISTTQEGTADIDWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLS 73
            ||.|||..:|.  ||..||||:||.|||||||||||:|||||||.||.|||.|||.:|:||.|||
Mosquito     7 LALLLLGWSTV--TAQKDWWESASFYQIYPRSFQDSNGDGIGDLNGIKSRLPYLKSLGMTAFWLS 69

  Fly    74 PIFTSPMSDFGYDISNFYDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVN 138
            ||:.|||:|||||||||.||.|.||||.||..|:.|||.|.::|||||||||||||:.||:|||.
Mosquito    70 PIYPSPMADFGYDISNFMDIHPSFGTLADFKQLVEEAKKLQLRIILDFVPNHSSDEHEWFKKSVQ 134

  Fly   139 REDGYDDFYVWDDGKLNEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPM 203
            |..||:|:|||.|.|...|   ||||:|||:.:.|..|.||::|:|::||||..||||||:.||.
Mosquito   135 RVSGYEDYYVWQDPKPGTE---RDPPNNWVAAWYGSAWEWNDERKQFYLHQFHKKQPDLNYRNPA 196

  Fly   204 VREHMLDVLKFWLDRGVDGFRIDAVPHIYEHRNADGSYPDEPVSGWGSDPNAYDYHDHIYTKDQP 268
            |.:.|.|||:||||:|||||||||||.::|    ...:|||||||..:||.:.:|..||||.|||
Mosquito   197 VVQAMKDVLRFWLDQGVDGFRIDAVPWLFE----TVGFPDEPVSGHSTDPLSQNYLTHIYTLDQP 257

  Fly   269 ATVDLMYEWREFLDNYRAQNGGDSRVLLAEAYSSVETLSAYFGNSTH-QGTQLPMNFQL-MYLSG 331
            .|||::|:|||.:|.|:.::...::||:.||:||::.:..||.:|.: ||:|:|.|||| |.|..
Mosquito   258 ETVDMVYQWRELMDQYKQEHNTTTKVLMTEAWSSLDVVKTYFNDSNNRQGSQMPFNFQLIMRLDQ 322

  Fly   332 YSTAKDVVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGA-HKVDLLNVIVNALPGASVTYY 395
            .|.|.|....|:.|::.:...| |.|||:||||..||:.|||. |.||::.:|...|||.:|||.
Mosquito   323 NSKASDFQTVINSWLDIIPPGH-TPNWVLGNHDKRRVSSRMGGDHMVDIMAMIELTLPGITVTYQ 386

  Fly   396 GEEIGMSNVDV-----------ECTGDSCED--RDGERTPMQWTAGKNADFSDGE-STWLPLSPE 446
            ||||||.:||:           :.|.::.::  ||..|||.||.:..||.|::.. ..||||:.:
Mosquito   387 GEEIGMHDVDISWADTQDPAACQLTEETYQEGTRDPARTPFQWDSTANAGFTNASVKPWLPLATD 451

  Fly   447 YQRYNVQTER-GVSRSSLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIRT-NKISEEY 509
            |...||:|:: ....|.:.:||.|..|:.::..:.    |.|....:.|.|..|:|: ......|
Mosquito   452 YPLVNVKTQQESAQNSHIKVFKELMNLRGTNTLIW----GSFKSLVLGENVYAILRSFPNDKRTY 512

  Fly   510 RILVNMGNGMEI-----LDGLAPKTYEYVLATAYSTHYSGQKADLSQRIILMPYEAVVL 563
            .:|.|:|:..||     ||...|....:.:.:..|.|.:|:.. .:..|:|.|||||||
Mosquito   513 VVLANIGSKSEIIDATKLDNSLPNELVFRVVSVSSNHITGESV-ATNNILLQPYEAVVL 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A2	NP_476625.2	AmyAc_maltase	24..484	CDD:200467	246/477 (52%)
LOC1280462	XP_320158.1	AmyAc_maltase	21..490	CDD:200467	247/480 (51%)