Protein Alignment Mal-A1 and malS

DIOPT Version :10

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_418028.1
• Gene: malS / 948088
• ECOCYCID: EG11316
• Length: 676
• Species: Escherichia coli
• Alignment Length: 599
• Identity: 121/599 - (20%)
• Similarity: 196/599 - (32%)
• Gaps: 218/599 - (36%)

  Fly    23 WESGNYYQIYPRSFRDSD----------GDGI--------GDLNGVTEKLQYLKDIGFTGTWLSP 69
            |.:...|.:....|.:.|          .||:        |||.|:|.||.||:.:|....|:|.
E. coli   186 WHNATVYFVLTDRFENGDPSNDQSYGRHKDGMAEIGTFHGGDLRGLTNKLDYLQQLGVNALWISA 250

  Fly    70 IFK--------SPMVDF------GYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNH 120
            .|:        ....||      ||...|:..:....|...|...::..|.:.||:|:.|.|.||
E. coli   251 PFEQIHGWVGGGTKGDFPHYAYHGYYTQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNH 315

  Fly   121 SSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGER----EPPS--NWNSEFRY------SAWE- 172
            :.    :.|.:...:..:...|:..| ::....|||    :|.:  .|:|...|      :.|:
E. coli   316 TG----YATLADMQEYQFGALYLSGD-EVKKSLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDK 375

  Fly   173 -W--NEVRQQYYLHQFAIQQADL-NYRNPA---------------------------VVNEM--- 203
             |  |.:|            .|: :|.||.                           ..|:|
E. coli   376 WWGKNWIR------------TDIGDYDNPGFDDLTMSLAFLPDIKTESTTASGLPVFYKNKMDTH 428

  Fly   204 ---------KNVIRFWLGK-----GVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDD 254
                     ::.:..||.:     |:.|||:|...:   |:|..:.|...|...
E. coli   429 AKAIDGYTPRDYLTHWLSQWVRDYGIDGFRVDTAKH---VELPAWQQLKTEASA----------- 479

  Fly   255 HCYTQHIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMT-EAYTSFENIMTYYGNGV----- 313
                             .:.:|::...:..::   ||...|| ||          :|:||
E. coli   480 -----------------ALREWKKANPDKALD---DKPFWMTGEA----------WGHGVMQSDY 514

  Fly   314 -RNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPE---GVYANWVLGNHDNKRVASRFGVQ 374
             |:|.....|||:.   ..|:||.:.:..:......|.|   |......|.:||     :|...:
E. coli   515 YRHGFDAMINFDYQ---EQAAKAVDCLAQMDTTWQQMAEKLQGFNVLSYLSSHD-----TRLFRE 571

  Fly   375 RTDLINILLQTLPGHAVTYNGEE----LGMTDVWISWEDTVDPNACNSDPDNYYARSRDPARSPY 435
            ..|....||...||....:.|:|    .|.|               .|||       ....||..
E. coli   572 GGDKAAELLLLAPGAVQIFYGDESSRPFGPT---------------GSDP-------LQGTRSDM 614

  Fly   436 QW-DASSKAGFTSADHTWLPVADDYKTNNALQQLRAPRSHLQIFKKLVRVRKEPSFRQGELNIQA 499
            .| |.|.|:. .|..| |          ..:.|.||....:...|:...:.|     ||...::.
E. coli   615 NWQDVSGKSA-ASVAH-W----------QKISQFRARHPAIGAGKQTTLLLK-----QGYGFVRE 662

  Fly   500 IDDD--VIIYSRQK 511
            ..||  :::::.|:
E. coli   663 HGDDKVLVVWAGQQ 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	118/580 (20%)
malS	NP_418028.1	malS	1..676	CDD:236543	120/597 (20%)