Protein Alignment Mal-A1 and IMA5

DIOPT Version :10

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_012319.1
• Gene: IMA5 / 853214
• SGDID: S000003752
• Length: 581
• Species: Saccharomyces cerevisiae
• Alignment Length: 577
• Identity: 174/577 - (30%)
• Similarity: 262/577 - (45%)
• Gaps: 117/577 - (20%)

  Fly    21 EWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDF 85
            :||:....|||||.||:||:.||.|||.|:|.||.|:|::|....|:.|.:.||..|.||||:::
Yeast     8 KWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANY 72

  Fly    86 YQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWF--TKSVDSDPVYKDFYIWHDGK 148
            .::.|.|||.||..:||.:|.:.|||:|:|.|.||.|.|:|||  ::|..::| .:|::.|...|
Yeast    73 EKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANP-KRDWFFWRPPK 136

  Fly   149 INNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVI-----R 208
            ..:|.|...||:||.|.|..|||.::|...:::||.||:.|.|.|:.|    .|.:..|     .
Yeast   137 GYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWEN----EECRKAIYDSSVG 197

  Fly   209 FWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSV----------NCPDPDDHCYTQHIY- 262
            :||...|.|||||......:|:     ..||.|:|:.:|          |.|...::....|.|
Yeast   198 YWLRHNVDGFRIDVGSMYSKVE-----GLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYM 257

  Fly   263 TQDMPE-----TIDMVYQWRELVDEFHVENG---GDKRLLMTEAYTSF-ENIMTYYGNGVRNGSH 318
            ...:||     |:..|....|  |:|.|...   |:..::....:||. ||....|       ..
Yeast   258 LSQVPEGKEIMTVGEVGIGNE--DDFRVYTSAKEGELNMMFNFKHTSVGENPKCKY-------EL 313

  Fly   319 IPFNF-DFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDNKRVASRFGVQ-------R 375
            |||.. ||..::   :::..::|:...|     ..:|    |.|||..|..||||..       .
Yeast   314 IPFTLKDFKLAL---AESFLFIENTDCW-----STIY----LENHDQPRSVSRFGSDSPKWREIS 366

  Fly   376 TDLINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPN---------ACNSDPDNYYA------ 425
            :.::..|:.:|.|....|.|:||||            ||         .|......|.|
Yeast   367 SKMLATLIISLTGTVFIYQGQELGM------------PNFKNRKIEQIKCVEGTGTYAAIKRDYG 419

  Fly   426 ---------------RSRDPARSPYQWDASS-KAGFTSADHTWLPVADDYKTN-NALQQLRAPRS 473
                           .|||..|:|:.|.|.. .|||:.....|:.:.:.::.. ||..:|:...|
Yeast   420 EDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFSKDAKPWIDMNESFRDGINAEAELKDKNS 484

  Fly   474 HLQIFKKLVRVRKEPS--FRQGELNIQAID---DDVIIYSRQKTGSDLYVIVLNLGS 525
            ....:||.::||||..  ...|. |.|.||   |.:.::::......::. |.|..|
Yeast   485 VFFFWKKALQVRKEHKDILVYGH-NFQFIDLDNDKLFMFTKDTDNKKMFA-VFNFSS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	166/543 (31%)
IMA5	NP_012319.1	AmyAc_SI_OligoGlu_DGase	11..498	CDD:200472	161/529 (30%)
		Malt_amylase_C	509..580	CDD:445893	7/32 (22%)