Protein Alignment Mal-A1 and IMA1

DIOPT Version :10

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_011803.3
• Gene: IMA1 / 853204
• SGDID: S000003519
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 172/567 - (30%)
• Similarity: 264/567 - (46%)
• Gaps: 98/567 - (17%)

  Fly    21 EWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDF 85
            :||:...:|||||.||:||:.||.||:.|:..||:|:|::|....|:||.:.||..|.||||:::
Yeast    13 KWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANY 77

  Fly    86 YQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWF--TKSVDSDPVYKDFYIWHDGK 148
            .::.|.|||.||...:|.|..::|:|.|.|.|.||.|:|:|||  ::|..::| .:|::.|...|
Yeast    78 EKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNP-KRDWFFWRPPK 141

  Fly   149 INNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEM-KNVIRFWLG 212
            ..:..|:..||:||.|.|..|||.::|..|::||..|...|.|||:.|......: ::.:.:||.
Yeast   142 GYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLD 206

  Fly   213 KGVSGFRIDAVPYLFE--VDLDRYNQYPDEPLT--NDSVNCPDPDDHCYTQ-----HIYTQDMPE 268
            .||.||||| |..|:.  |.|      ||.|:.  |.:....||    ||.     |.:.|:|.:
Yeast   207 HGVDGFRID-VGSLYSKVVGL------PDAPVVDKNSTWQSSDP----YTLNGPRIHEFHQEMNQ 260

  Fly   269 TI-DMVYQWRELVDEFHVENGGD--KRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSIN 330
            .| :.|...||::....:::..|  |||..:.:......:..:....|  |:...|.::.:..
Yeast   261 FIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSELFNFSHTDV--GTSPLFRYNLVPF-- 321

  Fly   331 NASKAGEYVEHIKKWMDAMPEGV-YAN----W---VLGNHDNKRVASRFG-------VQRTDLIN 380
                      .:|.|..|:.|.. |.|    |   .|.|||..|..:|||       |....|::
Yeast   322 ----------ELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLS 376

  Fly   381 ILLQTLPGHAVTYNGEELGMTDV--W--ISWEDTVDPNACNSDPDNYYAR--------------S 427
            :||..|.|....|.|:|||..:.  |  ..:||....|..|:..:.:...              |
Yeast   377 VLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALIS 441

  Fly   428 RDPARSPYQWDASS-KAGFTS-ADHTWLPVADDYKTN-NALQQLRAPRSHLQIFKKLVRVRKEPS 489
            ||.||:|.||.... .|||:. :...|..:.|.::.. |...:::.|.|.|..:|:.::.||
Yeast   442 RDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRK--- 503

  Fly   490 FRQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNLGSTSKTLDLTKYY 536
                      ...|:.:|     |.|...|.|:   ..|....||.|
Yeast   504 ----------AHKDITVY-----GYDFEFIDLD---NKKLFSFTKKY 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	162/525 (31%)
IMA1	NP_011803.3	AmyAc_SI_OligoGlu_DGase	16..503	CDD:200472	158/512 (31%)
		Malt_amylase_C	514..585	CDD:445893	7/22 (32%)