Protein Alignment Mal-A1 and MAL32

DIOPT Version :10

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_009858.3
• Gene: MAL32 / 852602
• SGDID: S000000503
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 627
• Identity: 177/627 - (28%)
• Similarity: 273/627 - (43%)
• Gaps: 132/627 - (21%)

  Fly    21 EWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDF 85
            :||:....|||||.||:||:.||.|||.|:|.||||:||:|....|:.|.:.||..|.|||||::
Yeast    12 KWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNY 76

  Fly    86 YQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWF--TKSVDSDPVYKDFYIWHDGK 148
            .::.|.|||.||...:|.|..::|:|.|.|.|.||.|||:|||  ::|..::| .:|::.|...|
Yeast    77 EKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNP-KRDWFFWRPPK 140

  Fly   149 INNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNP----AVVNEMKNVIRF 209
            ..:..|:..||:||.|.|..|||.::|...::||..||.:|.|||:.|.    |:   .::.:.|
Yeast   141 GYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAI---FESAVGF 202

  Fly   210 WLGKGVSGFRIDAVPYLFEVDLDRYNQ---YPDEPLTNDSVNCPDPDDHCYTQ---HIYTQDMPE 268
            ||..||.|||||..        ..|::   .||.|:.:.:.....|:...:..   |.|.|::..
Yeast   203 WLDHGVDGFRIDTA--------GLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHR 259

  Fly   269 TI-DMVYQWRELVDEFHVENGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNA 332
            .: :.|...||::....|.:|.|..|..:.|......:.::  ..|..|:...|.::.:...
Yeast   260 FMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF--THVELGTSPFFRYNIVPFT--- 319

  Fly   333 SKAGEYVEHIKKWMDAMPEGV--------YANWVLGNHDNKRVASRFGVQRT-------DLINIL 382
                     :|:|.:|:....        :|...:.|||..|..:||.....       .|:.:|
Yeast   320 ---------LKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLL 375

  Fly   383 LQTLPGHAVTYNGEELGMTDV--W--ISWEDTVDPNACNSDPDNYY------------------- 424
            ..:|.|....|.|:|:|..:.  |  ..:||.        |..|.|
Yeast   376 ECSLTGTLYVYQGQEIGQINFKEWPIEKYEDV--------DVKNNYEIIKKSFGKNSKEMKDFFK 432

  Fly   425 ---ARSRDPARSPYQWDASS-KAGFTSAD-HTWLPVADDYKTN-NALQQLRAPRSHLQIFKKLVR 483
               ..|||.:|:|..|.... .||||..| ..|..:.:.::.. |..|:.|...|.|..:|:.::
Yeast   433 GIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQ 497

  Fly   484 VRKEPSFRQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNLGSTSKTLDLTKYYE-------LGTQ 541
            .||:..             :::||     |.|...|.|:   :.:....||.||       |...
Yeast   498 ARKKYK-------------ELMIY-----GYDFQFIDLD---SDQIFSFTKEYEDKTLFAALNFS 541

  Fly   542 AEVITTSLSSQ----------YIDGDVIKSTEFVANPYVGTV 573
            .|.|..||..:          |.|.||   :..|..|:.|.:
Yeast   542 GEEIEFSLPREGASLSFILGNYDDTDV---SSRVLKPWEGRI 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	155/531 (29%)
MAL32	NP_009858.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	152/519 (29%)
		Malt_amylase_C	511..583	CDD:435493	19/76 (25%)