DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mal-A1 and SBE2.1

DIOPT Version :9

Sequence 1:	NP_476627.3	Gene:	Mal-A1 / 35824	FlyBaseID:	FBgn0002570	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_181180.1	Gene:	SBE2.1 / 818212	AraportID:	AT2G36390	Length:	858	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	116/559 - (20%)
Similarity:	200/559 - (35%)	Gaps:	149/559 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFK-SPMVDFGYDISDFYQIHPEYGTMEDF 98
            :|||             :.|..:|.:|:....:..|.: :....|||.:::|:.....:||.:|.
plant   347 NFRD-------------DVLPRIKKLGYNAVQIMAIQEHAYYASFGYHVTNFFAPSSRFGTPDDL 398

  Fly    99 ERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGEREPPSNWN 163
            :.:|.||.|:|:.:::|.|.:|:|      ..::|.    .|.:...||:..: :|.|.....|:
plant   399 KSLIDKAHELGLVVLMDIVHSHAS------KNTLDG----LDMFDGTDGQYFH-SGSRGYHWMWD 452

  Fly   164 SE-FRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVIRFWLGK-GVSGFRIDAVPYL 226
            |. |.|.:||                          |:..:.:..|:||.: ...|||.|.|..:
plant   453 SRLFNYGSWE--------------------------VLRYLLSNARWWLEEYKFDGFRFDGVTSM 491

  Fly   227 ------FEVDL-DRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDE-- 282
                  .:|:. ..||:|.......|:|             :|...:.:.|..:|....:|.|
plant   492 MYTHHGLQVEFTGNYNEYFGYSTDVDAV-------------VYLMLVNDLIHGLYPEAIVVGEDV 543

  Fly   283 -------FHVENGG---DKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNASKAGE 337
                   ..||:||   |.||.|..|....| ::.......:.|. |.|.   ||:.....|...
plant   544 SGMPAFCVPVEDGGVGFDYRLHMAVADKWIE-LLKKRDEDWQVGD-ITFT---LTNRRWGEKCVV 603

  Fly   338 YVEH----------IKKWMDAMPEGVYANWVLGNHDNKRVASRFGVQRTDLINILLQTLPGHA-V 391
            |.|.          |..|:  |.:.:|....:......||..  |:....:|.::...|.|.. :
plant   604 YAESHDQALVGDKTIAFWL--MDKDMYDFMAVDRQATPRVDR--GIALHKMIRLITMGLGGEGYL 664

  Fly   392 TYNGEELGMTDVWISWEDTVDPNACNSDPDNYYARSRDPARSPYQWDASSKAGFTSADHTWLPVA 456
            .:.|.|.|..: ||.:..|          |.:....|..|.:...:| ..:..|...|..:|...
plant   665 NFMGNEFGHPE-WIDFPRT----------DQHLPDGRVIAGNNGSYD-KCRRRFDLGDAEYLRYH 717

  Fly   457 DDYKTNNALQQLRAPRSHLQIFKKLVRVRKEPSFRQGELNIQAIDDDVIIYSRQKTGSDLYVIVL 521
            ...:.:.|:|.|......:....:.:..:.|             .|.||::.|   |:.|:  |.
plant   718 GLQEFDRAMQNLEETYGFMTSEHQYISRKDE-------------GDRVIVFER---GNLLF--VF 764

  Fly   522 NLGSTSKTLDLTKYYELGTQAEVITTSLSSQY---IDGD 557
            |...|:...|    |.:|       .|:..:|   :|.|
plant   765 NFHWTNSYSD----YRIG-------CSVPGKYKIVLDSD 792

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	100/493 (20%)
Mal-A1	NP_476627.3	Alpha-amylase	45..404	CDD:278554	83/391 (21%)
SBE2.1	NP_181180.1	PLN02447	150..830	CDD:215246	116/559 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910