Protein Alignment Mal-A1 and SLC3A2

DIOPT Version :9

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001012680.1
• Gene: SLC3A2 / 6520
• HGNCID: 11026
• Length: 631
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 126/601 - (20%)
• Similarity: 211/601 - (35%)
• Gaps: 193/601 - (32%)

  Fly     7 ACLLLAIVGFVG-------------------ATEWWESGNYYQIYPRSFRDSDGDGIGDLNGVTE 52
            |.|||..:|::|                   |.:||.:|..|:|  ...:...|.|.|:|.|:..
Human   185 ALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRI--GDLQAFQGHGAGNLAGLKG 247

  Fly    53 KLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFV 117
            :|.||..:...|..|.||.|:...|...  :|..||.|.:|:.|||:.::..||:..|::|||..
Human   248 RLDYLSSLKVKGLVLGPIHKNQKDDVAQ--TDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLT 310

  Fly   118 PNHSSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYL 182
            ||:.. ||.||:..||:
Human   311 PNYRG-ENSWFSTQVDT------------------------------------------------ 326

  Fly   183 HQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSV 247
                            |..::|:.:.|||..||.||::..:
Human   327 ----------------VATKVKDALEFWLQAGVDGFQVRDI------------------------ 351

  Fly   248 NCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTS-FENIMTYYGN 311
                            :::.:....:.:|:.:...|     .:.|||:....:| .:.|:
Human   352 ----------------ENLKDASSFLAEWQNITKGF-----SEDRLLIAGTNSSDLQQIL----- 390

  Fly   312 GVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDNKRVASRF-GVQR 375
                 |.:..|.|.|.:.:..|.:|...||.|..:..........|...:....|:.:.| ..|.
Human   391 -----SLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQL 450

  Fly   376 TDLINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPNACNSDPDNYYARSRDPARSPYQ-WDA 439
            ..|..::|.||||..|...|:|:|:                     :..|....|..:|.. ||.
Human   451 LRLYQLMLFTLPGTPVFSYGDEIGL---------------------DAAALPGQPMEAPVMLWDE 494

  Fly   440 SS---KAGFTSADHTWLPVADDYKTNNALQQLRAPRSHLQIFKKLVRVR-KEPSFRQGELNIQAI 500
            ||   ..|..||:.|....::|            |.|.|.:|::|...| ||.|...|:.:..:.
Human   495 SSFPDIPGAVSANMTVKGQSED------------PGSLLSLFRRLSDQRSKERSLLHGDFHAFSA 547

  Fly   501 DDDVIIYSRQKTGSDLYVIVLNLGSTS-----KTLDLTKYYELGTQAEVITTSLSSQ--YIDGDV 558
            ...:..|.|....::.:::|||.|...     :..||.....|..:|:::   ||:|  ..:|..
Human   548 GPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLL---LSTQPGREEGSP 609

  Fly   559 IKSTEFVANPYVGTVL 574
            ::.......|:.|.:|
Human   610 LELERLKLEPHEGLLL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	102/481 (21%)
		Alpha-amylase	45..404	CDD:278554	73/360 (20%)
SLC3A2	NP_001012680.1	SLC3A2_N	161..225	CDD:292647	10/39 (26%)
		AmyAc_SLC3A2	208..537	CDD:200483	101/485 (21%)
		AmyA	238..597	CDD:223443	106/513 (21%)
		DUF3459	520..625	CDD:288769	24/107 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820