Protein Alignment Mal-A1 and slc3a2

DIOPT Version :10

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_002941505.2
• Gene: slc3a2 / 493209
• XenbaseID: XB-GENE-1009245
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 136/613 - (22%)
• Similarity: 221/613 - (36%)
• Gaps: 208/613 - (33%)

  Fly     7 ACLLLAIVGFVG-------------------ATEWWESGNYYQI-YPRSFRDSDGDGIGDLNGVT 51
            |.|:|..:|:.|                   |.|||..|..||: .|.:|::   ||.|::..:.
 Frog    82 ALLILFWLGWAGMLAGAVVIIVQAPRCQPLPAMEWWNKGPLYQVGDPATFQE---DGAGNIQSIE 143

  Fly    52 EKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDF 116
            ::|:.|..:...|..:.||..:...:.  |.:....|.|.|||.|.|..::..|::..|:||||.
 Frog   144 KRLESLTSLKIKGLIIGPIHATKKDEI--DKTILTDIDPNYGTQEQFTSLLEAARKKSIQIILDL 206

  Fly   117 VPNHSSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYY 181
            .||:.| |..||.|:
 Frog   207 TPNYRS-EKSWFEKT-------------------------------------------------- 220

  Fly   182 LHQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDS 246
                     |:|:.     :.:|..|..||.:||.|
 Frog   221 ---------DINFE-----DNVKEAINTWLERGVGG----------------------------- 242

  Fly   247 VNCPDPDDHCYTQHIY---TQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTSFENIMTY 308
                          ||   ::::|.|.:.:|:|..:...|..|  |..|:|:..: .|.:|.:.
 Frog   243 --------------IYFGDSENLPNTSNFIYEWGNMTANFSKE--GKPRVLLLSS-NSTQNKLA- 289

  Fly   309 YGNGVRNGSHIPFN-------FDFLTSINN---ASKAGEYVEHIKKWMDAMPEGVYAN-WVLGNH 362
             ||         ||       :.||.:.|.   .|..|:..:::::      .|:..| |::|..
 Frog   290 -GN---------FNETDGILFYRFLDAENKKSFRSLGGDIKQYVEE------TGILGNSWMIGAP 338

  Fly   363 DNKRVASRFGVQRTDLINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPNACNSDPDNYYARS 427
            ....:||....:...:..:||.||||..::..|:|:|:.|:             .|.|    |:|
 Frog   339 QMGHMASLVNEKLFRVYQLLLFTLPGTPISLYGDEIGLKDL-------------PSKP----AQS 386

  Fly   428 RDPARSPYQWDASSKAGFTSADHTWLPVADDYKTNNALQQLRAPR-SHLQIFKKLVRVR-KEPSF 490
               :|...|||..|.|..:.      .:..|...|...:.....: |.|.|::||..:| ||.|.
 Frog   387 ---SRPNMQWDEVSVAANSP------QILSDVNANVTFKAQDTDKGSFLNIYRKLSDLRGKERSL 442

  Fly   491 RQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNL---GSTSKTLDLTKYYELGTQAEVITTSLSSQ 552
            ..||..:....|..|.:.|....::.||..||.   |....:|...:..||.....|:.:| |||
 Frog   443 LHGEFVLLYNSDKAIAFLRSWDQNERYVTALNFNYEGEVELSLKKDRGEELPEHGTVVLSS-SSQ 506

  Fly   553 YIDGDVI--KSTEFVAN-------PYVG 571
            ..:|:.:  ||.:..|.       ||.|
 Frog   507 RKEGESVSLKSLQLGAGEALLLKYPYSG 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	107/491 (22%)
slc3a2	XP_002941505.2	SLC3A2_N	52..123	CDD:464983	10/40 (25%)
		AmyAc_family	105..442	CDD:476817	105/495 (21%)